• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Pathological changes in muscle caused by haemorrhagic and proteolytic factors from Bothrops jararaca snake venom.

作者信息

Queiroz L S, Santo Neto H, Assakura M T, Reichl A P, Mandelbaum F R

出版信息

Toxicon. 1985;23(2):341-5. doi: 10.1016/0041-0101(85)90158-8.

DOI:10.1016/0041-0101(85)90158-8
PMID:3895580
Abstract

Haemorrhagic factor HF2 and bothropasin, two metalloproteins isolated from the venom of Bothrops jararaca, caused haemorrhage followed by myonecrosis and arterial necrosis after i.m. injection in mice. The effects of HF2 were qualitatively similar to those of bothropasin and crude B. jararaca venom, but its potency was about 20 times higher. The haemorrhagic and necrotizing actions of these components are unrelated to their proteolytic activity on casein.

摘要

相似文献

1
Pathological changes in muscle caused by haemorrhagic and proteolytic factors from Bothrops jararaca snake venom.
Toxicon. 1985;23(2):341-5. doi: 10.1016/0041-0101(85)90158-8.
2
Evaluation of three Brazilian antivenom ability to antagonize myonecrosis and hemorrhage induced by Bothrops snake venoms in a mouse model.在小鼠模型中评估三种巴西抗蛇毒血清对抗具窍蝮蛇蛇毒诱导的肌肉坏死和出血的能力。
Toxicon. 2007 Aug;50(2):196-205. doi: 10.1016/j.toxicon.2007.03.010. Epub 2007 Mar 24.
3
Effects of neutrophil depletion in the local pathological alterations and muscle regeneration in mice injected with Bothrops jararaca snake venom.中性粒细胞耗竭对注射了巴西矛头蝮蛇毒的小鼠局部病理改变和肌肉再生的影响。
Int J Exp Pathol. 2005 Apr;86(2):107-15. doi: 10.1111/j.0959-9673.2005.00419.x.
4
New insights into the structural elements involved in the skin haemorrhage induced by snake venom metalloproteinases.深入了解蛇毒金属蛋白酶诱导皮肤出血的结构要素。
Thromb Haemost. 2010 Sep;104(3):485-97. doi: 10.1160/TH09-12-0855. Epub 2010 Jul 20.
5
Proteolytic, edematogenic and myotoxic activities of a hemorrhagic metalloproteinase isolated from Bothrops alternatus venom.从阿根廷矛头蝮蛇毒中分离出的一种出血性金属蛋白酶的蛋白水解、致水肿和肌毒性活性。
Toxicon. 2005 Oct;46(5):546-54. doi: 10.1016/j.toxicon.2005.06.019.
6
Peptides derived from plasma proteins released by bothropasin, a metalloprotease present in the Bothrops jararaca venom.由矛头蝮蛇毒中存在的金属蛋白酶——矛头蝮蛋白酶释放的血浆蛋白衍生而来的肽。
Toxicon. 2017 Oct;137:65-72. doi: 10.1016/j.toxicon.2017.07.009. Epub 2017 Jul 8.
7
Identification of a linear B-cell epitope in the catalytic domain of bothropasin, a metalloproteinase from Bothrops jararaca snake venom.鉴定矛头蝮蛇（Bothrops jararaca）蛇毒金属蛋白酶 bothropasin 催化结构域中的线性 B 细胞表位。
Mol Immunol. 2018 Dec;104:20-26. doi: 10.1016/j.molimm.2018.10.019. Epub 2018 Nov 3.
8
Muscular lesions induced by a hemorrhagic factor from Bothrops neuwiedi snake venom.由纽氏矛头蝮蛇毒中的一种出血因子引起的肌肉损伤。
Braz J Med Biol Res. 1985;18(3):337-40.
9
[Proteolytic, hemorrhagic and myonecrotic effects of the venoms of Costa Rican snakes from the genera Bothrops, Crotalus and Lachesis (author's transl)].[矛头蝮属、响尾蛇属和睫角蝰属的哥斯达黎加蛇毒的蛋白水解、出血和肌坏死作用（作者译）]
Toxicon. 1980;18(3):315-21. doi: 10.1016/0041-0101(80)90011-2.
10
Hemorrhagic activity of Bothrops venoms determined by two different methods and relationship with proteolytic activity on gelatin and lethality.用两种不同方法测定的矛头蝮蛇毒的出血活性及其与对明胶的蛋白水解活性和致死性的关系。
Toxicon. 2003 Jun;41(8):949-58. doi: 10.1016/s0041-0101(02)00392-6.

引用本文的文献

1
Tissue damaging toxins in snake venoms: mechanisms of action, pathophysiology and treatment strategies.蛇毒中的组织损伤毒素：作用机制、病理生理学和治疗策略。
Commun Biol. 2024 Mar 22;7(1):358. doi: 10.1038/s42003-024-06019-6.
2
Comparative characterization of Viperidae snake venoms from Perú reveals two compositional patterns of phospholipase A expression.秘鲁蝰蛇科蛇毒的比较特征揭示了磷脂酶A表达的两种组成模式。
Toxicon X. 2020 May 30;7:100044. doi: 10.1016/j.toxcx.2020.100044. eCollection 2020 Sep.
3
Why is Skeletal Muscle Regeneration Impaired after Myonecrosis Induced by Viperid Snake Venoms?
为什么蝰蛇蛇毒诱导的肌肉坏死会导致骨骼肌再生受损？
Toxins (Basel). 2018 May 1;10(5):182. doi: 10.3390/toxins10050182.
4
Differential transcript profile of inhibitors with potential anti-venom role in the liver of juvenile and adult snake.在幼年和成年蛇肝脏中具有潜在抗蛇毒作用的抑制剂的差异转录谱。
PeerJ. 2017 Apr 27;5:e3203. doi: 10.7717/peerj.3203. eCollection 2017.
5
Effects of neutrophil depletion in the local pathological alterations and muscle regeneration in mice injected with Bothrops jararaca snake venom.中性粒细胞耗竭对注射了巴西矛头蝮蛇毒的小鼠局部病理改变和肌肉再生的影响。
Int J Exp Pathol. 2005 Apr;86(2):107-15. doi: 10.1111/j.0959-9673.2005.00419.x.
6
Purification, properties, and N-terminal amino acid sequence of a kallikrein-like enzyme from the venom of Lachesis muta rhombeata (Bushmaster).矛头蝮（巨蝮）毒液中一种类激肽释放酶的纯化、性质及N端氨基酸序列
J Protein Chem. 1997 Nov;16(8):809-18. doi: 10.1023/a:1026372018547.
7
Bothropstoxin-I: amino acid sequence and function.矛头蝮毒素-I：氨基酸序列与功能。
J Protein Chem. 1993 Feb;12(1):57-64. doi: 10.1007/BF01024915.
8
Neutralization of the oedematogenic activity of Bothrops jararaca venom on the mouse paw by an antibothropic fraction isolated from opossum (Didelphis marsupialis) serum.从负鼠（Didelphis marsupialis）血清中分离出的抗矛头蝮蛇毒组分对矛头蝮蛇毒致小鼠爪水肿活性的中和作用。
Agents Actions. 1992 Nov;37(3-4):250-9. doi: 10.1007/BF02028117.