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减重手术与肥胖患者全髋关节置换术结局改善相关:一项具有 6 年随访的全国队列研究。

Prior Bariatric Surgery Is Associated With Improved Total Hip Arthroplasty Outcomes in Patients Who Have Obesity: A National Cohort Study With 6 Years of Follow-Up.

机构信息

Department of Orthopaedics, UT Health San Antonio, San Antonio, Texas.

Department of Orthopaedics, Washington University School of Medicine, St. Louis, Missouri.

出版信息

J Arthroplasty. 2025 Jan;40(1):160-168. doi: 10.1016/j.arth.2024.06.065. Epub 2024 Jul 3.

DOI:10.1016/j.arth.2024.06.065
PMID:38969294
Abstract

BACKGROUND

Obesity is a risk factor for end-stage hip osteoarthritis. While total hip arthroplasty (THA) is commonly performed to reduce pain and improve function associated with osteoarthritis, obesity has been associated with an increased risk of complications after THA. Although bariatric surgery may also be utilized to reduce weight, the impact of bariatric surgery on THA outcomes remains inadequately understood.

METHODS

This retrospective cohort analysis utilized multicenter electronic medical record data ranging from 2003 to 2023. Patients who have obesity who underwent THA were stratified based on prior bariatric surgery. The final bariatric cohort comprised 451 patients after propensity score matching. Complication rates and revision risks were compared between cohorts at 6, 24, and 72 months. Additional analysis stratified patients by interval between bariatric surgery and THA.

RESULTS

At 6-month follow-up, the bariatric cohort had significantly lower risks of surgical site infection, wound dehiscence, and deep vein thrombosis (DVT). At 24 months, the bariatric cohort had a lower risk of DVT. At 72-month follow-up, the bariatric cohort had reduced rates of revision, mortality, cardiac morbidity, and Clavien-Dindo grade IV complications.

CONCLUSIONS

Obese patients who underwent bariatric surgery prior to THA experienced reduced medical complications at all time points and reduced rates of revision at 72 months relative to a matched cohort who did not undergo bariatric surgery.

摘要

背景

肥胖是终末期髋关节骨关节炎的一个危险因素。全髋关节置换术(THA)常用于减轻与骨关节炎相关的疼痛和改善功能,但肥胖与 THA 后并发症的风险增加有关。虽然减重手术也可用于减轻体重,但减重手术对 THA 结果的影响仍了解不足。

方法

本回顾性队列分析利用了 2003 年至 2023 年多中心电子病历数据。根据既往减重手术对接受 THA 的肥胖患者进行分层。经过倾向评分匹配后,最终的减重队列包括 451 例患者。在 6、24 和 72 个月时比较了两组的并发症发生率和翻修风险。另外还按减重手术和 THA 之间的间隔对患者进行了分层。

结果

在 6 个月的随访中,减重组手术部位感染、伤口裂开和深静脉血栓形成(DVT)的风险明显较低。在 24 个月时,减重组 DVT 的风险较低。在 72 个月的随访中,减重组的翻修率、死亡率、心脏发病率和 Clavien-Dindo 四级并发症发生率较低。

结论

与未行减重手术的匹配队列相比,THA 前接受减重手术的肥胖患者在所有时间点的医疗并发症发生率较低,72 个月时的翻修率也较低。

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Prior Bariatric Surgery Is Associated With Improved Total Hip Arthroplasty Outcomes in Patients Who Have Obesity: A National Cohort Study With 6 Years of Follow-Up.减重手术与肥胖患者全髋关节置换术结局改善相关:一项具有 6 年随访的全国队列研究。
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