Universidade Estadual Paulista (UNESP), Instituto de Ciência e Tecnologia e of Science and Technology, Câmpus São José dos Campos, São Paulo, Brazil.
Centro de Ciências Naturais e Humanas, Universidade Federal do ABC, Santo André, São Paulo, Brazil.
Clin Exp Dent Res. 2024 Aug;10(4):e926. doi: 10.1002/cre2.926.
Electronic nicotine delivery systems (e-cigarette, pod, and vape) are currently among the tobacco consumption of adolescents and young adults. The aim is to show oral mucosa and saliva alterations related to vape.
A vape-user patient, presenting a white plaque in the posterior region of the hard palate, underwent clinical examination, sialometry, pH evaluation, and excisional biopsy of the white lesion. Molecular changes in saliva and vape liquid were analyzed by vibrational spectroscopy.
The histopathological analyses showed hyperparakeratosis without dysplasia. Formaldehyde, ketones, and aromatic hydrocarbon species were identified in e-cig liquid by the FTIR.
The use of vape may be related to the development of hyperkeratotic lesions in the oral mucosa as well as significantly modify the patient's salivary patterns as the vape liquid presents carcinogenic and cytotoxic components in its composition.
电子烟（如烟、烟弹和 vape）是当前青少年和年轻人的烟草消费方式之一。本研究旨在展示与 vape 相关的口腔黏膜和唾液变化。
一名 vape 用户患者，硬腭后区出现白色斑块，接受了临床检查、唾液流率、pH 值评估以及白色病变的切除活检。通过振动光谱分析了唾液和 vape 液中的分子变化。
组织病理学分析显示无异型增生的过度角化。傅里叶变换红外光谱法（FTIR）鉴定电子烟液中存在甲醛、酮和芳烃。
电子烟的使用可能与口腔黏膜的过度角化病变的发展有关，并且由于电子烟液的组成中含有致癌和细胞毒性成分，因此会显著改变患者的唾液模式。
