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孟加拉国蔬菜中重金属的人体健康风险评估

Human health risk assessment of heavy metals in vegetables of Bangladesh.

机构信息

Department of Food Technology and Nutrition Science, Noakhali Science and Technology University, Noakhali, 3814, Bangladesh.

Department of Nutrition and Food Engineering, Daffodil International University, Savar, Dhaka, Bangladesh.

出版信息

Sci Rep. 2024 Jul 6;14(1):15616. doi: 10.1038/s41598-024-65734-6.

Abstract

This study aims to evaluate the heavy metal concentration in fifteen species of vegetables as well as associated health risk. Atomic absorption spectrometry is used to assess heavy metals. The mean concentrations of Pb, Cd, Cr, Ni and Fe in vegetables were 4.78, 0.713, 9.266, 0.083, 5.06 mg/kg/fw exceeding the reference value of FAO/WHO indicating unsafe to consumption. Based on principal component analysis, the Pb, Cr, Ni and Fe are from same sources. Health risk was estimated in terms of estimated daily intake (EDI), target hazard quotient, hazard index (HI) and cancer risk (CR). The EDI values of metals except Cr were found to be lower than maximum tolerable daily intake (MTDI). The total THQs of metals were > 1 indicating non-carcinogenic health risk. The individual HI values for vegetables except potato (0.831) and total HI values were found to be > 1 (94.747). The TCR of Pb, Cd and Cr were > 1.0E-04 which indicating carcinogenic risk. Fruit and pod vegetables contribute much in carcinogenic risk for Pb and Cr whereas fruit, root and stems vegetables for Cd. The study revealed potential human health risk associated with the consumption of different types of vegetables in Bangladeshi adult population that might assist the regulatory bodies to develop new strategies to minimize the risk to human.

摘要

本研究旨在评估 15 种蔬菜中的重金属浓度及其相关的健康风险。采用原子吸收光谱法来评估重金属。蔬菜中 Pb、Cd、Cr、Ni 和 Fe 的平均浓度分别为 4.78、0.713、9.266、0.083 和 5.06mg/kg/fw,超过了 FAO/WHO 的参考值,表明食用不安全。基于主成分分析,Pb、Cr、Ni 和 Fe 来自同一来源。根据估计每日摄入量(EDI)、目标危害系数、危害指数(HI)和癌症风险(CR)来评估健康风险。除了 Cr 之外,金属的 EDI 值均低于最大耐受日摄入量(MTDI)。金属的总 THQs>1,表明存在非致癌健康风险。除了马铃薯(0.831)外,蔬菜的个体 HI 值和总 HI 值均>1(94.747)。Pb、Cd 和 Cr 的 TCR>1.0E-04,表明存在致癌风险。水果和荚果类蔬菜对 Pb 和 Cr 的致癌风险贡献较大,而水果、根和茎类蔬菜对 Cd 的致癌风险贡献较大。本研究揭示了孟加拉国成年人群食用不同类型蔬菜所带来的潜在健康风险,这可能有助于监管机构制定新的策略来最大程度地降低对人类的风险。

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