少突胶质细胞染色质中的低重复长度。

A low repeat length in oligodendrocyte chromatin.

作者信息

Di Liegro I, Salemi G, Cestelli A

出版信息

J Neurochem. 1985 Oct;45(4):1006-12. doi: 10.1111/j.1471-4159.1985.tb05515.x.

DOI:10.1111/j.1471-4159.1985.tb05515.x

Abstract

The behavior of oligodendrocyte chromatin after micrococcal nuclease digestion of nuclei was assayed in brains of rats of four different ages. During oligodendrocyte differentiation, a decreasing sensitivity of the chromatin to enzymatic attack was observed. On the other hand, the nucleosomal repeat length showed a slight tendency to increase during development. It is worth noting that even the highest values reported here for "oligodendrocyte" chromatin repeat lengths are significantly lower than 200 base pairs, the value previously reported by others for "non-astrocytic glia."

摘要

在四种不同年龄大鼠的大脑中，检测了微球菌核酸酶消化细胞核后少突胶质细胞染色质的行为。在少突胶质细胞分化过程中，观察到染色质对酶攻击的敏感性降低。另一方面，核小体重复长度在发育过程中略有增加的趋势。值得注意的是，即使这里报道的“少突胶质细胞”染色质重复长度的最高值也显著低于200个碱基对，这是其他人先前报道的“非星形胶质细胞神经胶质”的值。