Aier Academy of Ophthalmology, Central South University, Changsha, China.
Hunan Province Optometry Engineering and Technology Research Centre, Changsha, China.
Ophthalmic Physiol Opt. 2024 Sep;44(6):1237-1247. doi: 10.1111/opo.13364. Epub 2024 Jul 9.
Defocus Incorporated Soft Contact (DISC) lenses, a commonly used type of multifocal lens in clinical practice, may slow down myopia progression by inducing myopic retinal defocus. The purpose of this study was to explore whether the induced defocus across the retina could be affected by visual environments encountered in the real world, such as differences in viewing distance and ambient illuminance.
In this cross-over trial, 30 myopic adults wore both DISC lenses and single vision contact (SVC) lenses in random order. An open-view Hartmann-Shack scanning wavefront sensor was used to measure defocus at different retinal locations along the horizontal meridian under four experimental conditions: far target (3 m) and near targets (0.33 m) under scotopic (<1 lux) or photopic (~300 lux) conditions.
The results showed that DISC lenses induced more myopic retinal defocus than SVC lenses in all conditions (all p < 0.05), except for the scotopic near target. In addition, for DISC lenses, the defocus was greater in the photopic than the scotopic conditions for both the far and near targets (both p < 0.05).
In conclusion, the retinal defocus induced by these multifocal lenses was dependent on both visual distance and ambient illuminance, indicating that the visual conditions might affect the anti-myopia efficacy of these devices.
离焦型软接触镜(DISC)是临床实践中常用的一种多焦点镜片,它通过诱导近视性视网膜离焦来减缓近视进展。本研究旨在探讨视网膜上的诱导离焦是否会受到现实世界中遇到的视觉环境的影响,例如视距和环境照度的差异。
在这项交叉试验中,30 名近视成年人以随机顺序同时佩戴 DISC 镜片和单视接触(SVC)镜片。使用开视哈特曼-夏克扫描波前传感器,在四种实验条件下测量水平子午线不同视网膜位置的离焦:远目标(3 米)和近目标(0.33 米),在暗视(<1 勒克斯)或明视(~300 勒克斯)条件下。
结果表明,在所有条件下(均 p<0.05),DISC 镜片比 SVC 镜片诱导的近视性视网膜离焦更多,除了暗视近目标。此外,对于 DISC 镜片,在远目标和近目标的明视条件下,离焦大于暗视条件(均 p<0.05)。
总之,这些多焦点镜片诱导的视网膜离焦既依赖于视觉距离,也依赖于环境照度,表明视觉条件可能会影响这些设备的抗近视效果。