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韩国原子弹爆炸幸存者队列中自我报告疾病的验证。

Validation of self-reported morbidities in the Korean Atomic Bomb Survivor Cohort.

作者信息

Jeong Ansun, Jeon Somin, Moon Seong-Geun, Kim Mi Kyung, Kim Inah, Kim Yu-Mi, Park Boyoung

机构信息

Department of Health Sciences, Hanyang University, Seoul, Korea.

Department of Preventive Medicine, Hanyang University College of Medicine, Seoul, Korea.

出版信息

Epidemiol Health. 2024;46:e2024058. doi: 10.4178/epih.e2024058. Epub 2024 Jun 28.

DOI:10.4178/epih.e2024058
PMID:38993111
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11826016/
Abstract

OBJECTIVES

This study aimed to evaluate the agreement of disease status collected through a survey of the Korean Atomic Bomb Survivor Cohort (K-ABC), compared with medical claim records from the Korean National Health Insurance Service (NHIS) database and the Korean Central Cancer Registry (KCCR).

METHODS

Data on the lifetime physician-diagnosed morbidities of 1,215 K-ABC participants were collected through an interviewer-administered questionnaire between 2020 and 2022. Survey data were linked to the NHIS and KCCR databases. Eleven diseases were included for validation. We evaluated the following indicators: sensitivity, specificity, positive predictive value, negative predictive value, accuracy, the area under the curve, and the kappa coefficient.

RESULTS

The mean±standard deviation age was 62.1±18.7 years, and 42.6% of the participants were aged ≥70 years. Hypertension and cataracts showed the highest prevalence rates (33.8 and 28.8%, respectively). Hypertension, diabetes, and cancer demonstrated high sensitivity (>0.8) and specificity (>0.9), whereas diabetes, cancer, myocardial infarction, angina pectoris, and asthma exhibited high accuracy (>0.9). In contrast, arthritis, allergic rhinitis, and asthma showed low sensitivity (<0.4) and kappa values (<0.3). In the participants aged ≥70 years, the kappa value was ≥0.4 for all diseases except arthritis, allergic rhinitis, and asthma.

CONCLUSIONS

The results from this initial analysis showed relatively high agreement between the survey and NHIS/KCCR databases, especially for hypertension, diabetes, and cancer. Our findings suggest that the information on morbidities collected through the questionnaires in this cohort was valid for both younger and older individuals.

摘要

目的

本研究旨在评估通过对韩国原子弹爆炸幸存者队列(K-ABC)进行调查收集的疾病状况与韩国国民健康保险服务(NHIS)数据库和韩国中央癌症登记处(KCCR)的医疗理赔记录之间的一致性。

方法

2020年至2022年期间,通过访员管理的问卷收集了1215名K-ABC参与者的终生医生诊断疾病数据。调查数据与NHIS和KCCR数据库相关联。纳入11种疾病进行验证。我们评估了以下指标:敏感性、特异性、阳性预测值、阴性预测值、准确性、曲线下面积和kappa系数。

结果

平均年龄±标准差为62.1±18.7岁,42.6%的参与者年龄≥70岁。高血压和白内障的患病率最高(分别为33.8%和28.8%)。高血压、糖尿病和癌症表现出高敏感性(>0.8)和特异性(>0.9),而糖尿病、癌症、心肌梗死、心绞痛和哮喘表现出高准确性(>0.9)。相比之下,关节炎、过敏性鼻炎和哮喘的敏感性较低(<0.4)且kappa值较低(<0.3)。在年龄≥70岁的参与者中,除关节炎、过敏性鼻炎和哮喘外,所有疾病的kappa值均≥0.4。

结论

这项初步分析的结果表明,调查与NHIS/KCCR数据库之间的一致性相对较高,尤其是对于高血压、糖尿病和癌症。我们的研究结果表明,通过该队列问卷调查收集的疾病信息对年轻人和老年人都是有效的。

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National Cancer Control Plan of the Korea: Current Status and the Fourth Plan (2021-2025).韩国国家癌症控制计划:现状与第四期计划(2021-2025)。
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Cohort Study Protocol: A Cohort of Korean Atomic Bomb Survivors and Their Offspring.
队列研究方案:韩国原子弹爆炸幸存者及其后代队列研究。
J Prev Med Public Health. 2023 Jan;56(1):1-11. doi: 10.3961/jpmph.22.469. Epub 2023 Jan 31.
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