Nurhayati Titing, Ridho Muhamad Farrel, Santoso Putri Teesa Radhiyanti, Setiawan Setiawan, Goenawan Hanna, Tarawan Vita Murniati
Department of Biomedical Science Faculty of Medicine Padjadjaran University, Bandung, Indonesia.
Faculty of Medicine Padjadjaran University, Bandung, Indonesia.
J Nutr Metab. 2024 Jul 4;2024:6815993. doi: 10.1155/2024/6815993. eCollection 2024.
Moringa leaves (), which are members of the Moringaceae family, are one of the herbal plants that are widely known in Indonesia. Phytochemical contents of moringa leaf, such as flavonoid, quercetin, and phenolic acid, are believed to have an effect on improvement of NAFLD. Therefore, moringa leaf is considered as one the herbal plants that can be used as supplementation in the form of adjuvant therapy to NAFLD. The study objective of our research is to review the effect of giving moringa leaf to the liver, especially the histopathologic features. This study will be conducted on literature review research design, more specifically in the form of a systematic review. . Five major electronic web databases, including PubMed, Cochrane Library, Google Scholar, Scopus, and ScienceDirect, were used in identifying literature from 2014 to 2023.
From a comprehensive analysis of 13 relevant literature sources, we elucidate the impact of leaf extract on liver histopathology, glucose, and lipid metabolism. Furthermore, we provide insights into its safety profile concerning human health.
The phytochemical content of leaf extract had shown a significant benefit in plant medicinal sector. From the research that had been done, leaf extract contributes to give significant improvement on liver histopathological features, glucose, and lipid metabolism on animal sample model.
辣木叶属于辣木科，是印度尼西亚广为人知的草药植物之一。辣木叶的植物化学成分，如黄酮类化合物、槲皮素和酚酸，被认为对改善非酒精性脂肪性肝病有作用。因此，辣木叶被视为可作为非酒精性脂肪性肝病辅助治疗形式的补充剂的草药植物之一。我们研究的目的是回顾给予辣木叶对肝脏的影响，特别是组织病理学特征。本研究将采用文献综述研究设计，更具体地说是系统评价的形式。使用包括PubMed、Cochrane图书馆、谷歌学术、Scopus和ScienceDirect在内的五个主要电子网络数据库来识别2014年至2023年的文献。
通过对13篇相关文献来源的综合分析，我们阐明了辣木叶提取物对肝脏组织病理学、葡萄糖和脂质代谢的影响。此外，我们提供了有关其对人类健康安全性的见解。
辣木叶提取物的植物化学成分在植物医药领域已显示出显著益处。从已开展的研究来看，辣木叶提取物对动物样本模型的肝脏组织病理学特征、葡萄糖和脂质代谢有显著改善作用。
