Department of Child Health, Division of Nephrology, Faculty of Medicine, Public Health and Nursing Universitas Gadjah Mada, Yogyakarta, Indonesia.
Department of Child Health, Division of Growth Development and Social Pediatric, Faculty of Medicine, Public Health and Nursing Universitas Gadjah Mada, Yogyakarta, Indonesia.
Saudi J Kidney Dis Transpl. 2023 Dec 1;34(Suppl 1):S66-S78. doi: 10.4103/sjkdt.sjkdt_231_22. Epub 2024 Jul 3.
Health-related quality of life (HRQOL) is an important patient-reported outcome. However, HRQOL research in pediatric patients with chronic kidney disease (CKD) in developing countries is limited. This cross-sectional study involved children with CKD who attended Dr. Sardjito General Hospital between January 2017 and September 2018. In total, 82 child-parent pairs were enrolled. Total HRQOL scores were significantly lower in children with Stages 3a-5 CKD than in children with Stages 1-2 CKD in the child (69.89 vs. 82.12, P = 0.004) and parent questionnaires (72.26 vs. 81.20, P = 0.02). The scores for the physical, school, and social function domains were significantly decreased. This study showed that children with Stages 3a-5 CKD had significantly lower HRQOL scores compared with children in the Stages 1-2 CKD group. Multidisciplinary teams can provide patient-centered and comprehensive management to optimize HRQOL scores during childhood and in future adult life.
健康相关生活质量（HRQOL）是一个重要的患者报告结果。然而，发展中国家儿童慢性肾脏病（CKD）患者的 HRQOL 研究有限。本横断面研究纳入了 2017 年 1 月至 2018 年 9 月期间在 Sardjito 综合医院就诊的 CKD 患儿及其家长。共纳入 82 对患儿-家长。与 CKD 1-2 期患儿相比，CKD 3a-5 期患儿的总 HRQOL 评分在儿童（69.89 对 82.12，P=0.004）和家长问卷（72.26 对 81.20，P=0.02）中显著降低。身体、学校和社会功能领域的评分显著下降。本研究表明，与 CKD 1-2 期患儿相比，CKD 3a-5 期患儿的 HRQOL 评分明显较低。多学科团队可以提供以患者为中心的全面管理，以优化儿童期和未来成年期的 HRQOL 评分。
