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糖尿病性骨丢失:骨质疏松症。

Bone Loss in Diabetes Mellitus: Diaporosis.

机构信息

Department of Internal Medicine, Albert Szent-Györgyi Medical School, University of Szeged, 6703 Szeged, Hungary.

Department of Oral Biology and Experimental Dental Research, Faculty of Dentistry, University of Szeged, 6703 Szeged, Hungary.

出版信息

Int J Mol Sci. 2024 Jul 2;25(13):7269. doi: 10.3390/ijms25137269.

Abstract

The objective of this review is to examine the connection between osteoporosis and diabetes, compare the underlying causes of osteoporosis in various forms of diabetes, and suggest optimal methods for diagnosing and assessing fracture risk in diabetic patients. This narrative review discusses the key factors contributing to the heightened risk of fractures in individuals with diabetes, as well as the shared elements impacting the treatment of both diabetes mellitus and osteoporosis. Understanding the close link between diabetes and a heightened risk of fractures is crucial in effectively managing both conditions. There are several review articles of meta-analysis regarding diaporosis. Nevertheless, no review articles showed collected and well-organized medications of antidiabetics and made for inconvenient reading for those who were interested in details of drug mechanisms. In this article, we presented collected and comprehensive charts of every antidiabetic medication which was linked to fracture risk and indicated plausible descriptions according to research articles.

摘要

本次综述的目的在于探讨骨质疏松症与糖尿病之间的关联,比较不同类型糖尿病中导致骨质疏松症的潜在原因,并为糖尿病患者的诊断和骨折风险评估提出最佳方法。本综述讨论了导致糖尿病患者骨折风险升高的关键因素,以及影响糖尿病和骨质疏松症治疗的共同因素。了解糖尿病与骨折风险升高之间的密切联系对于有效管理这两种疾病至关重要。有几篇关于骨质疏松症的荟萃分析综述文章。然而,没有一篇综述文章收集并整理了抗糖尿病药物,并使其难以阅读,对于那些对药物机制细节感兴趣的人来说尤其不方便。在本文中,我们呈现了与骨折风险相关的每一种抗糖尿病药物的收集和综合图表,并根据研究文章给出了合理的描述。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d07/11242219/d623790194c1/ijms-25-07269-g001.jpg

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