将在线自适应放射治疗应用于标准C型臂直线加速器。
Bringing online adaptive radiotherapy to a standard C-arm linac.
作者信息
Groot Koerkamp Maureen L, Bol Gijsbert H, Kroon Petra S, Krikke Lean L, Harderwijk Tessa, Zoetelief Annelies J, Scheeren Annick, van der Vegt Stefan, Plat Annika, Hes Jochem, van Gasteren Ineke B A, Renders Esmee R T, Rutgers Reijer H A, Kok Saskia W, van Kaam Joost, Schimmel-de Kogel Geja J, Sikkes Gonda G, Winkel Dennis, van Rijssel Michael J, Wopereis André J M, Ishakoglu Kübra, Noteboom Juus L, van der Voort van Zyp Jochem R N, Beck Naomi, Soeterik Timo F W, van de Pol Sandrine M G, Eppinga Wietse S C, van Es Corine A, Raaymakers Bas W
机构信息
Department of Radiotherapy, UMC Utrecht, Heidelberglaan 100, 3584CX Utrecht, the Netherlands.
出版信息
Phys Imaging Radiat Oncol. 2024 Jun 7;31:100597. doi: 10.1016/j.phro.2024.100597. eCollection 2024 Jul.
Current online adaptive radiotherapy (oART) workflows require dedicated equipment. Our aim was to develop and implement an oART workflow for a C-arm linac which can be performed using standard clinically available tools. A workflow was successfully developed and implemented. Three patients receiving palliative radiotherapy for bladder cancer were treated, with 33 of 35 total fractions being delivered with the cone-beam computed tomography (CBCT)-guided oART workflow. Average oART fraction duration was 24 min from start of CBCT acquisition to end of beam on. This work shows how oART could be performed without dedicated equipment, broadening oART availability for application at existing treatment machines.
当前的在线自适应放疗（oART）工作流程需要专用设备。我们的目标是为C形臂直线加速器开发并实施一种oART工作流程，该流程可使用标准的临床可用工具来执行。一种工作流程已成功开发并实施。对三名接受膀胱癌姑息性放疗的患者进行了治疗，总共35次分次中有33次采用了锥形束计算机断层扫描（CBCT）引导的oART工作流程。从CBCT采集开始到束流关闭，oART分次的平均持续时间为24分钟。这项工作展示了如何在不使用专用设备的情况下进行oART，拓宽了oART在现有治疗机器上的应用范围。
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