Gao Yuxin, Wang Xu, Fan Cunyi
Department of Orthopedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
College of Fisheries and Life Science, Shanghai Ocean University, Shanghai, China.
iScience. 2024 Jun 8;27(7):110214. doi: 10.1016/j.isci.2024.110214. eCollection 2024 Jul 19.
Two-dimensional (2D) materials, especially graphene-based materials, have important implications for tissue regeneration and biomedicine due to their large surface area, transport properties, ease of functionalization, biocompatibility, and adsorption capacity. Despite remarkable progress in the field of tissue regeneration and biomedicine, there are still problems such as unclear long-term stability, lack of experimental data, and detection accuracy. This paper reviews recent applications of graphene-based materials in tissue regeneration and biomedicine and discusses current issues and prospects for the development of graphene-based materials with respect to promoting the regeneration of tendons, neuronal cells, bone, chondrocytes, blood vessels, and skin, as well as applications in sensing, detection, anti-microbial activity, and targeted drug delivery.
二维（2D）材料，尤其是基于石墨烯的材料，因其具有大表面积、传输特性、易于功能化、生物相容性和吸附能力，在组织再生和生物医学领域具有重要意义。尽管在组织再生和生物医学领域取得了显著进展，但仍存在诸如长期稳定性不明、缺乏实验数据以及检测准确性等问题。本文综述了基于石墨烯的材料在组织再生和生物医学中的最新应用，并讨论了基于石墨烯的材料在促进肌腱、神经元细胞、骨骼、软骨细胞、血管和皮肤再生方面以及在传感、检测、抗菌活性和靶向药物递送等应用方面的当前问题和发展前景。
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