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骨组织再生中的石墨烯基材料:前景与挑战

Graphene Family Materials in Bone Tissue Regeneration: Perspectives and Challenges.

作者信息

Cheng Xinting, Wan Qianbing, Pei Xibo

机构信息

State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, No. 14, Section 3, South Peoples Road, Chengdu, 610041, China.

Department of Prosthodontics, West China Hospital of Stomatology, Sichuan University, No. 14, Section 3, South Peoples Road, Chengdu, 610041, China.

出版信息

Nanoscale Res Lett. 2018 Sep 18;13(1):289. doi: 10.1186/s11671-018-2694-z.

DOI:10.1186/s11671-018-2694-z
PMID:30229504
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6143492/
Abstract

We have witnessed abundant breakthroughs in research on the bio-applications of graphene family materials in current years. Owing to their nanoscale size, large specific surface area, photoluminescence properties, and antibacterial activity, graphene family materials possess huge potential for bone tissue engineering, drug/gene delivery, and biological sensing/imaging applications. In this review, we retrospect recent progress and achievements in graphene research, as well as critically analyze and discuss the bio-safety and feasibility of various biomedical applications of graphene family materials for bone tissue regeneration.

摘要

近年来,我们见证了石墨烯基材料在生物应用研究方面取得了丰硕的突破。由于其纳米级尺寸、大比表面积、光致发光特性和抗菌活性,石墨烯基材料在骨组织工程、药物/基因递送以及生物传感/成像应用方面具有巨大潜力。在本综述中,我们回顾了石墨烯研究的最新进展和成果,并对石墨烯基材料在骨组织再生的各种生物医学应用的生物安全性和可行性进行了批判性分析和讨论。

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