Krishnakumari Parvathy Krishnan, Bakker Hannah, Lahrichi Nadia, Côté Fannie L, Gromicho Joaquim, Govindakarnavar Arunkumar, Jha Priya, Shrestha Saugat, Mulmi Rashmi, Bhusal Nirajan, Stapith Deepesh, Jha Runa, Shrestha Lilee, Samuel Reuben, Naidoo Dhamari, Del Rio Vilas Victor
Amsterdam Business School, University of Amsterdam, Amsterdam, The Netherlands.
Karlsruhe Institute of Technology, Karlsruhe, Germany.
Lancet Reg Health Southeast Asia. 2024 Jul 1;27:100436. doi: 10.1016/j.lansea.2024.100436. eCollection 2024 Aug.
Ensuring equitable physical access to SARS-CoV-2 testing has proven to be crucial for controlling the COVID-19 epidemic, especially in countries like Nepal with its challenging terrain. During the second wave of the pandemic in May 2021, there was immense pressure to expand the laboratory network in Nepal to ensure calibration of epidemic response. The expansion led to an increase in the number of testing facilities from 69 laboratories in May 2021 to 89 laboratories by November 2021. We assessed the equity of physical access to COVID-19 testing facilities in Nepal during 2021. Furthermore, we investigated the potential of mathematical optimisation in improving accessibility to COVID-19 testing facilities.
Based on up-to-date publicly available data sets and on the COVID-19-related daily reports published by Nepal's Ministry of Health and Population from May 1 to November 15, 2021, we measured the disparities in geographical accessibility to COVID-19 testing across Nepal at a resolution of 1 km. In addition, we proposed an optimisation model to prescribe the best possible locations to set up testing laboratories maximizing access, and tested its potential impact in Nepal.
The analysis identified vulnerable districts where, despite ramping up efforts, physical accessibility to testing facilities remains low under two modes of travel-walking and motorized driving. Both geographical accessibility and its equality were better under the motorised mode compared with the walking mode. If motorised transportation were available to everyone, the population coverage within 60 min of any testing facility (public and private) would be close to threefold the coverage for pedestrians within the same hour: 61.4% motorised against 22.2% pedestrian access within the hour, considering the whole population of Nepal. Very low accessibility was found in most areas except those with private test centres concentrated in the capital city of Kathmandu. The hypothetical use of mathematical optimisation to select 20 laboratories to add to the original 69 could have improved access from the observed 61.4% offered by the laboratories operating in November to 71.4%, if those 20 could be chosen optimally from all existing healthcare facilities in Nepal. In mountainous terrain, accessibility is very low and could not be improved, even considering all existing healthcare facilities as potential testing locations.
The findings related to geographical accessibility to COVID-19 testing facilities should provide valuable information for health-related planning in Nepal, especially in emergencies where data might be limited and decisions time-sensitive. The potential use of publicly available data and mathematical optimisation could be considered in the future.
WHO Special Programme for Research and Training in Tropical Diseases (TDR).
事实证明,确保公平获取严重急性呼吸综合征冠状病毒2(SARS-CoV-2)检测对于控制2019冠状病毒病(COVID-19)疫情至关重要,尤其是在像尼泊尔这样地形复杂的国家。在2021年5月的第二波疫情期间,尼泊尔面临着巨大压力,需要扩大实验室网络以确保疫情应对的校准。这一扩张使得检测设施的数量从2021年5月的69个实验室增加到2021年11月的89个实验室。我们评估了2021年尼泊尔获取COVID-19检测设施的实际公平性。此外,我们还研究了数学优化在改善获取COVID-19检测设施方面的潜力。
基于最新的公开数据集以及尼泊尔卫生与人口部于2021年5月1日至11月15日发布的与COVID-19相关的每日报告,我们以1公里的分辨率测量了尼泊尔全国范围内获取COVID-19检测的地理可达性差异。此外,我们提出了一个优化模型,以规定设立检测实验室的最佳位置,从而最大限度地提高可达性,并测试了其在尼泊尔的潜在影响。
分析确定了一些脆弱地区,尽管加大了努力,但在步行和机动车驾驶这两种出行方式下,获取检测设施的实际可达性仍然很低。与步行模式相比,机动车模式下的地理可达性及其平等性都更好。如果每个人都能使用机动车,那么在任何检测设施(公立和私立)60分钟内的人口覆盖率将接近同一小时内行人覆盖率的三倍:考虑到尼泊尔的总人口,一小时内机动车可达率为61.4%,而行人可达率为22.2%。除了首都加德满都有集中的私人检测中心的地区外,大多数地区的可达性都非常低。如果能从尼泊尔所有现有的医疗设施中最优地选择20个实验室加入原有的69个实验室,那么通过数学优化的假设使用,可将11月运营的实验室所提供的可达率从观察到的61.4%提高到71.4%。在山区,可达性非常低,即使将所有现有的医疗设施都视为潜在的检测地点,也无法得到改善。
与获取COVID-19检测设施的地理可达性相关的研究结果应为尼泊尔的卫生相关规划提供有价值的信息,尤其是在数据可能有限且决策时间紧迫的紧急情况下。未来可考虑潜在地使用公开数据和数学优化方法。
世界卫生组织热带病研究和培训特别规划(TDR)