• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Microglia as potential key regulators in viral-induced neuroinflammation.

作者信息

Ismail Fatme Seval, Faustmann Timo Jendrik, Faustmann Pedro M, Corvace Franco

机构信息

Department of Neurology, Klinikum Vest, Academic Teaching Hospital of the Ruhr University Bochum, Recklinghausen, Germany.

Department of Psychiatry and Psychotherapy, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany.

出版信息

Front Cell Neurosci. 2024 Jul 11;18:1426079. doi: 10.3389/fncel.2024.1426079. eCollection 2024.

DOI:10.3389/fncel.2024.1426079
PMID:39055547
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11269195/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b96/11269195/6beeb7751c5e/fncel-18-1426079-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b96/11269195/6beeb7751c5e/fncel-18-1426079-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b96/11269195/6beeb7751c5e/fncel-18-1426079-g0001.jpg

相似文献

1
Microglia as potential key regulators in viral-induced neuroinflammation.小胶质细胞作为病毒诱导神经炎症中潜在的关键调节因子。
Front Cell Neurosci. 2024 Jul 11;18:1426079. doi: 10.3389/fncel.2024.1426079. eCollection 2024.
2
Targeting innate immunity for neurodegenerative disorders of the central nervous system.针对中枢神经系统神经退行性疾病的先天性免疫治疗
J Neurochem. 2016 Sep;138(5):653-93. doi: 10.1111/jnc.13667.
3
Innate immunity and neuroinflammation in the CNS: the role of microglia in Toll-like receptor-mediated neuronal injury.先天免疫和中枢神经系统中的神经炎症:小胶质细胞在 Toll 样受体介导的神经元损伤中的作用。
Glia. 2010 Feb;58(3):253-63. doi: 10.1002/glia.20928.
4
Glial cells suppress postencephalitic CD8+ T lymphocytes through PD-L1.神经胶质细胞通过程序性死亡配体1(PD-L1)抑制脑炎后CD8 + T淋巴细胞。
Glia. 2014 Oct;62(10):1582-94. doi: 10.1002/glia.22701. Epub 2014 Jun 3.
5
NG2 glia regulate brain innate immunity via TGF-β2/TGFBR2 axis.NG2 胶质细胞通过 TGF-β2/TGFBR2 轴调节大脑固有免疫。
BMC Med. 2019 Nov 15;17(1):204. doi: 10.1186/s12916-019-1439-x.
6
Microglia-mediated neuroinflammation is an amplifier of virus-induced neuropathology.小胶质细胞介导的神经炎症是病毒诱导的神经病理学的放大器。
J Neurovirol. 2014 Apr;20(2):122-36. doi: 10.1007/s13365-013-0188-4. Epub 2013 Aug 27.
7
Inhibition of the JAK/STAT Pathway Protects Against α-Synuclein-Induced Neuroinflammation and Dopaminergic Neurodegeneration.抑制JAK/STAT信号通路可预防α-突触核蛋白诱导的神经炎症和多巴胺能神经退行性变。
J Neurosci. 2016 May 4;36(18):5144-59. doi: 10.1523/JNEUROSCI.4658-15.2016.
8
Differential transcriptional profiles identify microglial- and macrophage-specific gene markers expressed during virus-induced neuroinflammation.差异转录谱鉴定了病毒诱导的神经炎症期间表达的小胶质细胞和巨噬细胞特异性基因标记物。
J Neuroinflammation. 2019 Jul 20;16(1):152. doi: 10.1186/s12974-019-1545-x.
9
Hypoxia inducible factor-1α regulates microglial innate immune memory and the pathology of Parkinson's disease.缺氧诱导因子-1α 调节小胶质细胞固有免疫记忆和帕金森病的病理。
J Neuroinflammation. 2024 Mar 30;21(1):80. doi: 10.1186/s12974-024-03070-2.
10
Receptors, Channel Proteins, and Enzymes Involved in Microglia-mediated Neuroinflammation and Treatments by Targeting Microglia in Ischemic Stroke.参与小胶质细胞介导的神经炎症的受体、通道蛋白和酶以及缺血性中风中靶向小胶质细胞的治疗方法。
Neuroscience. 2021 Apr 15;460:167-180. doi: 10.1016/j.neuroscience.2021.02.018. Epub 2021 Feb 18.

引用本文的文献

1
A bioinformatic analysis to systematically unveil shared pathways and molecular mechanisms underlying monkeypox and its predominant neurological manifestations.一项生物信息学分析,旨在系统揭示猴痘及其主要神经学表现背后的共同途径和分子机制。
Front Cell Infect Microbiol. 2025 Jul 2;15:1506687. doi: 10.3389/fcimb.2025.1506687. eCollection 2025.
2
Revisiting the Pathogenesis of X-Linked Adrenoleukodystrophy.重新审视X连锁肾上腺脑白质营养不良的发病机制。
Genes (Basel). 2025 May 17;16(5):590. doi: 10.3390/genes16050590.
3
Polyphenols and miRNA interplay: a novel approach to combat apoptosis and inflammation in Alzheimer's disease.

本文引用的文献

1
Astrocytes in human central nervous system diseases: a frontier for new therapies.人类中枢神经系统疾病中的星形胶质细胞:新疗法的前沿。
Signal Transduct Target Ther. 2023 Oct 13;8(1):396. doi: 10.1038/s41392-023-01628-9.
2
Viral-induced neuroinflammation: Different mechanisms converging to similar exacerbated glial responses.病毒诱导的神经炎症:不同机制汇聚成相似的加剧性胶质细胞反应。
Front Neurosci. 2023 Mar 2;17:1108212. doi: 10.3389/fnins.2023.1108212. eCollection 2023.
3
Role of SARS-CoV-2 Spike-Protein-Induced Activation of Microglia and Mast Cells in the Pathogenesis of Neuro-COVID.
多酚与微小RNA的相互作用:对抗阿尔茨海默病细胞凋亡和炎症的新方法。
Front Aging Neurosci. 2025 May 7;17:1571563. doi: 10.3389/fnagi.2025.1571563. eCollection 2025.
4
Cytokine Profile Analysis During Sialodacryoadenitis Virus and Mouse Hepatitis Virus JHM Strain Infection in Primary Mixed Microglia and Astrocyte Culture-Preliminary Research.原发性混合小胶质细胞和星形胶质细胞培养中涎泪腺炎病毒和小鼠肝炎病毒JHM株感染期间的细胞因子谱分析——初步研究
Cells. 2025 Apr 25;14(9):637. doi: 10.3390/cells14090637.
SARS-CoV-2 刺突蛋白诱导小胶质细胞和肥大细胞激活在神经 COVID 发病机制中的作用。
Cells. 2023 Feb 22;12(5):688. doi: 10.3390/cells12050688.
4
Microglia states and nomenclature: A field at its crossroads.小胶质细胞状态和命名:一个处于十字路口的领域。
Neuron. 2022 Nov 2;110(21):3458-3483. doi: 10.1016/j.neuron.2022.10.020.
5
Longitudinal analysis reveals high prevalence of Epstein-Barr virus associated with multiple sclerosis.纵向分析显示,多发性硬化症与 Epstein-Barr 病毒的高患病率相关。
Science. 2022 Jan 21;375(6578):296-301. doi: 10.1126/science.abj8222. Epub 2022 Jan 13.
6
Microglia: Immune and non-immune functions.小胶质细胞:免疫和非免疫功能。
Immunity. 2021 Oct 12;54(10):2194-2208. doi: 10.1016/j.immuni.2021.09.014.
7
The Influence of Virus Infection on Microglia and Accelerated Brain Aging.病毒感染对小胶质细胞和加速大脑衰老的影响。
Cells. 2021 Jul 20;10(7):1836. doi: 10.3390/cells10071836.
8
Dysregulation of brain and choroid plexus cell types in severe COVID-19.重症 COVID-19 中脑和脉络丛细胞类型的失调。
Nature. 2021 Jul;595(7868):565-571. doi: 10.1038/s41586-021-03710-0. Epub 2021 Jun 21.
9
Reactive astrocyte nomenclature, definitions, and future directions.反应性星形胶质细胞命名、定义和未来方向。
Nat Neurosci. 2021 Mar;24(3):312-325. doi: 10.1038/s41593-020-00783-4. Epub 2021 Feb 15.
10
Neuropathobiology of COVID-19: The Role for Glia.新型冠状病毒肺炎的神经病理生物学:神经胶质细胞的作用
Front Cell Neurosci. 2020 Nov 11;14:592214. doi: 10.3389/fncel.2020.592214. eCollection 2020.