School of Nursing and Midwifery, Faculty of Health, University of Plymouth, Plymouth, UK.
Paediatric Immunology, Infectious Diseases & Allergy, Great North Children's Hospital, Newcastle Upon Tyne, UK.
BMJ Paediatr Open. 2024 Jul 29;8(1):e002737. doi: 10.1136/bmjpo-2024-002737.
There is a need to empower parents and carers of young infants to recognise signs of serious illness and to act on these appropriately. Compiling the signs and symptoms of serious illness in infants found in clinical guidelines will support the evidence-based update of the 30+-year-old content of the Baby Check App to empower parents and carers.
To systematically review clinical guidelines for signs and symptoms related to serious illness in infants aged 6 months and below.
A rapid review was carried out by searching PubMed, CINAHL, NICE, Cochrane and Embase for clinical guidelines reporting signs and symptoms of serious illness in young infants. The time period was restricted from 2018 to 2023. Only guidelines published in English were included.
Fourteen clinical guidelines from 2307 retrieved articles were reviewed. Sixty signs and symptoms indicative of serious illness in infants were identified from the clinical guidelines. The guidelines originated from the UK (n=9, 65%), Italy (n=1, 7%), South Africa (n=1, 7%), Switzerland (n=1, 7%), USA (n=1, 7%), UK and USA (n=1, 7%). The 10 most frequent signs and symptoms were decreased consciousness, tachypnoea, looks seriously unwell to a health professional, high fever, central cyanosis, apnoea, seizures, frequent vomiting, non-blanching rash and noisy breathing.
Knowledge of the most frequently occurring signs and symptoms that were found in the reviewed guidelines will contribute to the update of the content of the Baby Check App. This will ensure that guidance for parents and carers is consistent with the current evidence base.
需要赋予婴幼儿的父母和照顾者识别严重疾病迹象并适当地采取行动的能力。整理出临床指南中婴儿严重疾病的体征和症状，将支持对已有 30 多年历史的 Baby Check App 内容进行基于证据的更新，以赋予父母和照顾者权力。
系统评价与 6 个月及以下婴儿严重疾病相关的临床指南中有关体征和症状的内容。
通过检索 PubMed、CINAHL、NICE、Cochrane 和 Embase，对报告婴幼儿严重疾病体征和症状的临床指南进行快速综述。时间范围限定为 2018 年至 2023 年。仅纳入发表英文版本的指南。
从 2307 篇检索文章中，有 14 篇临床指南被纳入综述。从临床指南中确定了 60 个提示婴儿严重疾病的体征和症状。这些指南来自英国（n=9，65%）、意大利（n=1，7%）、南非（n=1，7%）、瑞士（n=1，7%）、美国（n=1，7%）、英国和美国（n=1，7%）。10 个最常见的体征和症状是意识减退、呼吸急促、专业医护人员认为患儿病情严重、高热、中央性发绀、呼吸暂停、抽搐、频繁呕吐、不褪色皮疹和呼吸声粗重。
了解从综述指南中发现的最常见体征和症状，将有助于更新 Baby Check App 的内容。这将确保为父母和照顾者提供的指导与当前的证据基础保持一致。
