Toonen L S J, van Swaaij B W M, Timmerman M F, Van der Weijden Fridus G A, Slot D E
Department of Periodontology Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Department of Dental Hygiene Hogeschool Arnhem Nijmegen (HAN), University of Applied Sciences, Nijmegen, The Netherlands.
Int J Dent Hyg. 2025 Feb;23(1):153-163. doi: 10.1111/idh.12842. Epub 2024 Jul 29.
To assess user perceptions of different commercially available fluoride mouthwashes (FL-MWs).
A single-blind, randomized clinical trial was conducted. Participants were randomly assigned to a sequence of six different FL-MWs, one of which contained alcohol. For each visit, participants rinsed with one specific mouthwash (15 mL) for 30 s. After rinsing, participants completed a questionnaire with a visual analogue scale. Questions focused on overall taste, mild/pungent feeling, taste duration, foaming effect, burning sensation, sensitivity, numbness, dryness, rinsing time, smell, and colour of the mouthwashes. Descriptive analyses and statistical tests regarding differences among and between the mouthwashes were performed.
Overall, 53 participants completed the study protocol, including nine who did, however, not rinse with the alcohol-containing mouthwash due to religious reasons. Among the mouthwashes, significant differences were found for foaming effect, sensitivity, rinsing time, smell, and colour (p < 0.05). Pairwise comparison for smell did not reveal a difference, and foaming was within the acceptance range (low to medium foaming). Coloured mouthwashes were more appreciated than transparent solutions (p = 0.00). The mouthwash containing essential oils and alcohol produced significantly more sensitivity (p = 0.00) and, in general, participants experienced the rinsing time significantly longer (p < 0.05) compared to the non-alcohol-containing mouthwashes.
There is heterogeneity in user perceptions and preferences for FL-MWs, with a significant difference in foaming effect, sensitivity, rinsing time, smell, and colour. Coloured mouthwashes are preferred. The mouthwash containing essential oils and alcohol was less acceptable in relation to sensitivity and rinsing time.
评估用户对不同市售含氟漱口水（FL-MWs）的看法。
进行了一项单盲随机临床试验。参与者被随机分配使用六种不同的含氟漱口水，其中一种含有酒精。每次就诊时，参与者用一种特定的漱口水（15毫升）漱口30秒。漱口后，参与者完成一份带有视觉模拟量表的问卷。问题集中在总体味道、温和/刺鼻感、味道持续时间、起泡效果、灼烧感、敏感度、麻木感、干燥感、漱口时间、气味和漱口水颜色上。对漱口水之间和漱口水内部的差异进行了描述性分析和统计检验。
总体而言，53名参与者完成了研究方案，不过其中9人因宗教原因未使用含酒精的漱口水漱口。在漱口水之间，发现起泡效果、敏感度、漱口时间、气味和颜色存在显著差异（p<0.05）。气味的两两比较未显示差异，且起泡在可接受范围内（低至中等起泡）。有色漱口水比透明溶液更受欢迎（p=0.00）。与不含酒精的漱口水相比，含精油和酒精的漱口水产生的敏感度显著更高（p=0.00），而且总体而言，参与者的漱口时间明显更长（p<0.05）。
用户对含氟漱口水的看法和偏好存在异质性，在起泡效果、敏感度、漱口时间、气味和颜色方面存在显著差异。有色漱口水更受青睐。含精油和酒精的漱口水在敏感度和漱口时间方面不太容易被接受。
