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量子尺寸碳点的抗癌活性:机遇与挑战

Anticancer activity of quantum size carbon dots: opportunities and challenges.

作者信息

Bhattacharya Tanima, Preetam Subham, Mukherjee Sohini, Kar Sanjukta, Roy Debanjan Singha, Singh Harshita, Ghose Arak, Das Tanmoy, Mohapatra Gautam

机构信息

Faculty of Applied Science, Lincoln University College, 47301, Petaling Jaya, Selangor Darul Ehsan, Malaysia.

Department of Robotics and Mechatronics Engineering, Daegu Gyeongbuk Institute of Science and Technology (DGIST), Daegu, 42988, Republic of Korea.

出版信息

Discov Nano. 2024 Aug 5;19(1):122. doi: 10.1186/s11671-024-04069-7.

Abstract

Research into the anticancer activity of quantum-sized carbon dots (CDs) has emerged as a promising avenue in cancer research. This CDs delves into the opportunities and challenges associated with harnessing the potential of these nanostructures for combating cancer. Quantum-sized carbon dots, owing to their unique physicochemical properties, exhibit distinct advantages as potential therapeutic agents. Opportunities lie in their tunable size, surface functionalization capabilities, and biocompatibility, enabling targeted drug delivery and imaging in cancer cells. However, we include challenges, a comprehensive understanding of the underlying mechanisms, potential toxicity concerns, and the optimization of synthesis methods for enhanced therapeutic efficacy. A succinct summary of the state of the research in this area is given in this review, emphasizing the exciting possibilities and ongoing challenges in utilizing quantum-sized carbon dots as a novel strategy for cancer treatment.

摘要

量子尺寸碳点(CDs)的抗癌活性研究已成为癌症研究中一条充满希望的途径。本文深入探讨了利用这些纳米结构的潜力对抗癌症所带来的机遇和挑战。量子尺寸碳点由于其独特的物理化学性质,作为潜在的治疗剂具有明显优势。机遇在于其可调节的尺寸、表面功能化能力和生物相容性,能够实现癌细胞中的靶向药物递送和成像。然而,挑战包括对潜在机制的全面理解、潜在的毒性问题以及优化合成方法以提高治疗效果。本综述简要总结了该领域的研究现状,强调了利用量子尺寸碳点作为癌症治疗新策略的令人兴奋的可能性和持续存在的挑战。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ead0/11300426/bb0510df0cbb/11671_2024_4069_Fig1_HTML.jpg

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