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一种新鉴定出的细菌,其表型与嗜肺军团菌相似,但基因不同:肺炎病例中的一株分离菌。

A newly identified bacterium phenotypically resembling, but genetically distinct from, Legionella pneumophila: an isolate in a case of pneumonia.

作者信息

Lewallen K R, McKinney R M, Brenner D J, Moss C W, Dail D H, Thomason B M, Bright R A

出版信息

Ann Intern Med. 1979 Dec;91(6):831-4. doi: 10.7326/0003-4819-91-6-831.

Abstract

A bacterium with growth characteristics similar to, but genetically distinct from, either Legionella pneumophila or WIGA (a "rickettsia-like agent") was obtained from a postmortem lung specimen of a patient with fatal atypical pneumonia at the M. D. Anderson Hospital and Tumor Institute in Houston, Texas. This bacterium and WIGA have essentially the same cellular fatty acid composition, which is distinct from that of L. pneumophila. Deoxyribonucleic acid-reletadness studies show that the isolate from Texas is only about 10% related to both L. pneumophila and WIGA and there fore may represent a new species. This new bacterium should be considered in selecting laboratory procedures in the diagnosis of atypical pneumonia.

摘要

从得克萨斯州休斯敦市MD安德森医院和肿瘤研究所一名死于非典型肺炎患者的尸检肺标本中,获得了一种细菌,其生长特性与嗜肺军团菌或WIGA(一种“类立克次氏体病原体”)相似,但在基因上有所不同。这种细菌与WIGA具有基本相同的细胞脂肪酸组成,这与嗜肺军团菌不同。脱氧核糖核酸相关性研究表明,来自得克萨斯州的分离株与嗜肺军团菌和WIGA的相关性仅约为10%,因此可能代表一个新物种。在选择非典型肺炎诊断的实验室程序时,应考虑这种新细菌。

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