Suppr超能文献

受自然启发的创新:用于可持续抗菌和二氧化碳固定的藻酸-曲酸材料。

Nature-inspired innovation: Alginic-kojic acid material for sustainable antibacterial and carbon dioxide fixation.

机构信息

Department of Drug and Health Sciences, University of Catania, Viale Andrea Doria 6, 95125 Catania, Italy.

Department of Drug and Health Sciences, University of Catania, Viale Andrea Doria 6, 95125 Catania, Italy; Department of Biomedical and Biotechnological Sciences (Biometec), University of Catania, Via Santa Sofia 97, 95123 Catania, Italy.

出版信息

Int J Biol Macromol. 2024 Oct;277(Pt 4):134514. doi: 10.1016/j.ijbiomac.2024.134514. Epub 2024 Aug 5.

Abstract

The current environmental consciousness of the world's population encourages researchers to work on new materials that are environmentally benign and able to display the appropriate features for the needed application. To develop high-performing, inexpensive eco-materials, scientists have frequently turned to nature, attempting to mimic its processes' excellent performance at a reasonable price. In this regard, we decided to focus on alginic acid (AA), a polysaccharide widely found in brown algae, and kojic acid (KA), a chelating agent fungi produces. This study proposes rapidly synthesizing a sustainable, biocompatible material (AK) based on AA and KA, employing chlorokojic acid (CKA). The material has a dual function: antibacterial activity on both Gram-positive and Gram-negative bacteria, without any cytotoxic action on human cells in vitro, and catalytic ability to convert CO into cyclic carbonates at atmospheric pressure, without solvents, with high yields, and without the use of metals. Furthermore, the material's insolubility in organic solvents allows it to be easily separated from the reaction product and reused for other catalytic cycles. Both applications have a key role in the medical and environmental fields, combating the outbreak of infections and providing an innovative methodology to fix the CO on specific substrates.

摘要

当前世界人口的环境意识促使研究人员致力于开发对环境友好且能够展现所需应用适当特性的新材料。为了开发高性能、低成本的生态材料,科学家们经常向大自然寻求灵感,试图以合理的价格模仿其卓越的过程性能。在这方面,我们决定专注于褐藻中广泛存在的多糖酸(AA)和真菌产生的螯合剂曲酸(KA)。本研究提出了一种基于 AA 和 KA 的快速合成可持续、生物相容材料(AK)的方法,使用氯曲酸(CKA)。该材料具有双重功能:对革兰氏阳性菌和革兰氏阴性菌均具有抗菌活性,对体外人类细胞没有任何细胞毒性作用,并且能够在大气压下将 CO 催化转化为环状碳酸酯,无需溶剂,产率高,并且不使用金属。此外,该材料不溶于有机溶剂,因此可以很容易地从反应产物中分离出来,并在其他催化循环中重复使用。这两种应用在医学和环境领域都具有关键作用,可用于对抗感染的爆发,并提供一种将 CO 固定在特定底物上的创新方法。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验