Liang Zheng-Wei, Guan Yan-Hui, Lv Zheng, Yang Sheng-Chao, Zhang Guang-Hui, Zhao Yin-He, Zhao Ming, Chen Jun-Wen
College of Agronomy and Biotechnology & The Key Laboratory of Medicinal Plant Biology of Yunnan Province & National Local Joint Engineering Research Center on Germplasm Innovation and Utilization of Chinese Medicinal Materials in Southwestern China, Yunnan Agricultural University, Kunming 650201, People's Republic of China.
Yunnan Characteristic Plant Extraction Laboratory, Kunming 650201, People's Republic of China.
Food Chem X. 2024 Jul 14;23:101642. doi: 10.1016/j.fochx.2024.101642. eCollection 2024 Oct 30.
and are important economic plants that utilize dried roots for medicinal and food dual purposes; there is still insufficient research of their stems and leaves, which also contain triterpenoid saponins. The extraction process was developed with a total saponin content of 12.30 ± 0.34% and 12.19 ± 0.64% for (PNL) and (PQL) extracts, respectively. PNL and PQL saponin extracts showed good antioxidant, antihypertensive, hypoglycemic, and anti-inflammatory properties in vitro and RAW264.7 cells. A total of 699 metabolites were identified in PNL and PQL saponin extracts, with the majority being triterpenoid saponins, flavonoids and amino acids. Fourteen ginsenosides, 18 flavonoids or alkaloids, and 16 amino acids were enriched in both saponin extracts. Overall, the utilization of saponins from medicinal plants PNL and PQL has been developed to facilitate systematic research in the functional food and natural product industries.
[植物名称1]和[植物名称2]是重要的经济作物,其干燥根可用于药用和食用双重目的;对它们的茎叶研究仍不充分,而茎叶中也含有三萜皂苷。所开发的提取工艺得到的[植物名称1](PNL)提取物和[植物名称2](PQL)提取物的总皂苷含量分别为12.30±0.34%和12.19±0.64%。PNL和PQL皂苷提取物在体外及RAW264.7细胞中表现出良好的抗氧化、降压、降血糖和抗炎特性。在PNL和PQL皂苷提取物中共鉴定出699种代谢物,其中大部分为三萜皂苷、黄酮类化合物和氨基酸。两种皂苷提取物中均富集了14种人参皂苷、18种黄酮类或生物碱以及16种氨基酸。总体而言,已开展了对药用植物PNL和PQL中皂苷的利用研究,以促进功能食品和天然产物行业的系统研究。