Panpisut Piyaphong, Toneluck Arnit, Khamsuk Chutikarn, Channasanon Somruethai, Tanodekaew Siriporn, Monmaturapoj Naruporn, Naruphontjirakul Parichart
Faculty of Dentistry, Thammasat University, Pathum Thani, 12120, Thailand.
Thammasat University Research Unit in Dental and Bone Substitute Biomaterials, Thammasat University, Pathum Thani, 12120, Thailand.
Heliyon. 2024 Jul 14;10(14):e34512. doi: 10.1016/j.heliyon.2024.e34512. eCollection 2024 Jul 30.
This study aimed to develop resin coatings containing monocalcium phosphate monohydrate (MCPM), Sr/F-doped bioactive glass (Sr/F-BAGs), and pre-reacted glass ionomer fillers (SPG) that enhance ion release without detrimentally affecting the mechanical properties of GIC. The objective of this study was to evaluate the degree of monomer conversion (DC), biaxial flexural strength, surface microhardness, and ion release of the GICs coated with experimental coating materials compared to a commercial product (EQUIA Coat, EC). Four experimental resin coating materials containing 10-20 wt% of MCPM with Sr/F-BAGs and 5-10 wt% SPG were prepared. The DC of the coating material was determined using ATR-FTIR. The flexural strength and surface microhardness of the coated GICs were assessed. Fluoride and elemental (Ca,P,Sr,Si,Al) release were measured using fluoride-specific electrodes and ICP-OES. The DC of the experimental coating material (60-69 %) was higher than that of EC (55 %). The strength of GICs coated with experimental materials (35-40 MPa) was comparable to EC (37 MPa). However, their surface microhardness (13-24 VHN) was lower than EC (44 VHN). The experimental coating materials reduced fluoride release by ∼43 %, similar to EC (∼40 %). However, experimental coating materials promoted higher P and Sr release than EC. In conclusion, GICs coated with the experimental resin coating containing ion-releasing additives exhibited mechanical properties similar to those of the commercial product. The new coating materials promoted a higher level of ion release for GICs. These properties could potentially enhance remineralizing actions for the coated GICs.
本研究旨在开发含有一水磷酸二氢钙(MCPM)、锶/氟掺杂生物活性玻璃(Sr/F-BAGs)和预反应玻璃离子填料(SPG)的树脂涂层,该涂层可增强离子释放,同时不会对玻璃离子粘固剂(GIC)的机械性能产生不利影响。本研究的目的是评估与市售产品(EQUIA Coat,EC)相比,涂覆有实验性涂层材料的GIC的单体转化率(DC)、双轴弯曲强度、表面显微硬度和离子释放情况。制备了四种含有10-20 wt% MCPM与Sr/F-BAGs以及5-10 wt% SPG的实验性树脂涂层材料。使用ATR-FTIR测定涂层材料的DC。评估涂覆GIC的弯曲强度和表面显微硬度。使用氟特异性电极和ICP-OES测量氟化物和元素(钙、磷、锶、硅、铝)释放。实验性涂层材料的DC(60-69%)高于EC(55%)。涂覆有实验材料的GIC的强度(35-40 MPa)与EC(37 MPa)相当。然而,它们的表面显微硬度(13-24 VHN)低于EC(44 VHN)。实验性涂层材料使氟化物释放降低了约43%,与EC(约40%)相似。然而,实验性涂层材料促进了比EC更高的磷和锶释放。总之,涂覆有含离子释放添加剂的实验性树脂涂层的GIC表现出与市售产品相似的机械性能。新型涂层材料促进了GIC更高水平的离子释放。这些特性可能会增强涂覆GIC的再矿化作用。