Attal Camille, Demoury Benjamin, Reimbold Pierre, Mensah Aurore, Lescaille Géraldine, Rochefort Juliette
Oral and Dental Medicine Department Pitié Salpetrière Hospital, Paris Cité University Paris France.
Anatomy and Pathology Department Sorbonne University Paris France.
Clin Case Rep. 2024 Aug 7;12(8):e9253. doi: 10.1002/ccr3.9253. eCollection 2024 Aug.
The purpose of this article is to highlight that oral Kaposi's disease can be indicative of a high viral load of HIV, either in the case of primary infection or therapeutic failure.
We report two cases of Kaposi Disease associated with HIV. The first case was a 30-year-old patient who unaware of her HIV-positive status, and who was diagnosed with AIDS stage because of the biopsy revealed a gingival location of Kaposi disease. The second case was a 34-year-old patient who was referred to our department with a history of palatal lesion and claimed at first having no previous known medical conditions although his overall health condition seemed deteriorated. Our clinical examination was evocative of Kaposi Disease, which was confirmed by an emergency blood assessment and histological examination. Our diagnosis led us to disclose the HIV-positive status of the patient and identify a progression to the AIDS stage, which allowed us to reintroduce the patient in the hospital framework. This case emphasizes the role of the oral surgeon as a key actor thanks to their knowledge of the clinical buccal manifestations of sexually transmitted infections (STI), in an era of resurgence of those conditions in vulnerable key populations.
本文旨在强调，无论是在初次感染还是治疗失败的情况下，口腔卡波西肉瘤都可能提示HIV病毒载量较高。
我们报告了两例与HIV相关的卡波西肉瘤病例。第一例是一名30岁的患者，她不知道自己HIV呈阳性，因活检显示卡波西肉瘤位于牙龈而被诊断为艾滋病期。第二例是一名34岁的患者，因腭部病变前来我科就诊，起初声称既往无已知病史，但其整体健康状况似乎恶化。我们的临床检查提示为卡波西肉瘤，紧急血液评估和组织学检查证实了这一诊断。我们的诊断促使我们披露患者的HIV阳性状态，并确定其已进展至艾滋病期，从而得以将患者重新纳入医院治疗体系。在性传播感染（STI）在脆弱重点人群中再度流行的时代，该病例凸显了口腔外科医生凭借其对性传播感染临床口腔表现的了解所发挥的关键作用。
