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反流发现评分和反流症状指数:喉咽反流疾病诊断与管理的潜在指标

Reflux Finding Score and Reflux Symptom Index Potential Indicators for Diagnosis and Management of Laryngopharyngeal Reflux Disease.

作者信息

Prakash M D, T Linna Natious, Joy Lyra

机构信息

Department of E.N.T., Bangalore Medical College and Research Institute, K. R. Road, Bangalore, 560002 India.

Department of E.N.T., Sree Mookambika Institute of Medical Sciences, Kulasekharam, Kanyakumari 629161 India.

出版信息

Indian J Otolaryngol Head Neck Surg. 2024 Aug;76(4):3239-3244. doi: 10.1007/s12070-024-04657-0. Epub 2024 Apr 20.

Abstract

Retrograde movement of gastric contents into the pharynx is termed Laryngopharyngeal Reflux (LPR). It represents an extraesophageal manifestation associated with gastroesophageal reflux disease (GERD). The objective of the study is to investigate the clinical profile of LPR and its response to treatment. Three hundred consecutive patients who presented to the ENT outpatient department with a clinical profile of LPR were selected. The patients' symptoms were assessed using the Reflux Symptom Index (RSI), followed by an endoscopic examination of the larynx and scoring using the Reflux Finding Score (RFS). Patients were started on LPR treatment if they had an RSI score of 13 and an RFS of more than 7. The patients were then started on medication and monitored for three months. The most common symptom in our research sample (52%) was a foreign body sensation in the throat. On endoscopic examination of the larynx, the most common sign was hyperemia/erythema of laryngeal tissue, especially bilateral arytenoids. Most of our patients responded favorably to a combination of pantoprazole (40 mg) and domperidone (30 mg) for 4 weeks. This was measured by the reduction in RSI and RFS scores. LPR is a frequently encountered clinical entity, and otorhinolaryngologists should consider it when treating patients with chronic symptoms such as throat pain and voice changes. Appropriate LPR diagnosis and care can help prevent unnecessary prescriptions for antibiotics and surgical interventions in these patients.

摘要

胃内容物逆行进入咽部被称为喉咽反流(LPR)。它是一种与胃食管反流病(GERD)相关的食管外表现。本研究的目的是调查LPR的临床特征及其对治疗的反应。选取了连续300例以LPR临床特征就诊于耳鼻喉科门诊的患者。使用反流症状指数(RSI)评估患者症状,随后对喉部进行内镜检查并使用反流发现评分(RFS)进行评分。如果患者的RSI评分为13且RFS大于7,则开始进行LPR治疗。然后患者开始用药并监测三个月。在我们的研究样本中,最常见的症状(52%)是喉咙有异物感。在内镜检查喉部时,最常见的体征是喉组织充血/红斑,尤其是双侧杓状软骨。我们的大多数患者对泮托拉唑(40毫克)和多潘立酮(30毫克)联合使用4周反应良好。这通过RSI和RFS评分的降低来衡量。LPR是一种常见的临床病症,耳鼻喉科医生在治疗有喉咙痛和声音改变等慢性症状的患者时应考虑到这一点。适当的LPR诊断和护理有助于避免对这些患者不必要的抗生素处方和手术干预。

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