Macdonald J B
Clin Geriatr Med. 1985 Aug;1(3):621-36.
Drugs can contribute to falls in the elderly. Older people have more diseases, take more medications, and more frequently have drug side effects. Current studies show that the link between drugs and falls is best illustrated by the barbiturates, and well founded with phenothiazines and tricyclic antidepressants. The more types of drugs a patient receives, the greater the likelihood of a fall. Combining drugs with various diseases adds to the risk. New research should concentrate on naming individual drugs in larger surveys of falling. Much more sophisticated statistical procedures and testing would allow analysis of the specific dangers of drug and drug/disease combinations.
药物会促使老年人跌倒。老年人疾病更多,服用的药物更多,且更常出现药物副作用。目前的研究表明,巴比妥类药物最能说明药物与跌倒之间的联系,而吩噻嗪类药物和三环类抗抑郁药也有充分依据。患者接受的药物种类越多,跌倒的可能性就越大。药物与各种疾病并存会增加风险。新的研究应集中在更大规模的跌倒调查中指明具体药物。更为精密复杂的统计程序和测试将有助于分析药物以及药物与疾病组合的具体风险。