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短期多组分运动训练可改善绝经后妇女的执行功能。

Short-term multicomponent exercise training improves executive function in postmenopausal women.

机构信息

Faculty of Medicine, Master Degree on Sport, Exercise and Health Sciences, Airlangga University, Surabaya, Indonesia.

Faculty of Medicine, Department of Public Health and Preventive Medicine, Airlangga University, Surabaya, Indonesia.

出版信息

PLoS One. 2024 Aug 14;19(8):e0307812. doi: 10.1371/journal.pone.0307812. eCollection 2024.

Abstract

Declined cognitive function is commonly complained during the menopausal transition and continues afterward. Combining different exercises potentially leads to greater improvements in cognitive function, however, evidence of the benefits that accrue with multicomponent exercise training, specifically for postmenopausal women is limited. Therefore, this study aimed to investigate the effects of short-term multicomponent exercise training programs on executive function in postmenopausal women. Thirty women (59.8 ± 5.2 years), who were at least 12 months post menopause were allocated into a control (CON) group and an exercise (EX) training group. The EX group underwent a 2-week (five times/week) multicomponent exercise program comprising aerobic, strength, flexibility, and balance exercises for 40-60 min. Executive function was assessed by using the Stroop test and global cognitive function was assessed using the Mini-Mental State Examination (MMSE) at baseline (pre) and after 2 weeks (post) of exercise. The EX group showed improved performance in the Stroop test, with faster inhibition reaction time (ES (g) = 0.76; p = 0.039) and fewer errors across all tasks (color naming: g = 0.8, p = 0.032; word reading: g = 0.88, p = 0.019; inhibition: g = 0.99, p = 0.009; switching: g = 0.93, p = 0.012) following exercise intervention. Additionally, statistical analysis of the MMSE score showed a significant improvement (g = 1.27; p = 0.001). In conclusion, our findings suggest that a short-term multicomponent exercise program improves selective tasks of executive function in postmenopausal women along with global cognitive function. Trial registration ISRCTN13086152.

摘要

认知功能下降在绝经过渡期经常被抱怨,并持续存在。结合不同的运动可能会导致认知功能的更大改善,然而,多成分运动训练带来的益处的证据是有限的,特别是对于绝经后妇女。因此,本研究旨在调查短期多成分运动训练方案对绝经后妇女执行功能的影响。30 名女性(59.8±5.2 岁),绝经至少 12 个月,被分配到对照组(CON)和运动组(EX)。EX 组接受了为期 2 周(每周 5 次)的多成分运动方案,包括有氧、力量、灵活性和平衡运动,持续 40-60 分钟。使用 Stroop 测试评估执行功能,使用简易精神状态检查(MMSE)评估整体认知功能,在基线(pre)和运动 2 周后(post)进行评估。EX 组在 Stroop 测试中表现出更好的成绩,抑制反应时间更快(ES(g)=0.76;p=0.039),所有任务的错误更少(颜色命名:g=0.8,p=0.032;单词阅读:g=0.88,p=0.019;抑制:g=0.99,p=0.009;转换:g=0.93,p=0.012)。此外,MMSE 评分的统计分析显示有显著改善(g=1.27;p=0.001)。总之,我们的发现表明,短期多成分运动方案可改善绝经后妇女执行功能的选择性任务以及整体认知功能。试验注册 ISRCTN8510133。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f3fc/11324113/ca17ddd80eca/pone.0307812.g001.jpg

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