Yin Q L, Yu X, Li X, Fang B, Zhang X L, Peng M W, Ye G J, Liu L L
Provincial Academy of Preventive Medicine, Hubei Provincial Center for Disease Control and Prevention, Wuhan 430079, China.
Zhonghua Yu Fang Yi Xue Za Zhi. 2024 Aug 6;58(8):1129-1134. doi: 10.3760/cma.j.cn112150-20240111-00044.
To analyze the epidemiological characteristics of human respiratory syncytial virus (HRSV) in patients with acute respiratory infection (ARIs) in sentinel hospitals of the Hubei influenza surveillance network from 2016 to 2023. ARIs samples [including influenza-like cases (ILI) and severe acute respiratory infection (SARI)] were collected from influenza surveillance sentinel hospitals in Hubei Province from 2016 to 2023, and case information was collected. HRSV virus nucleic acid typing was performed by fluorescence quantitative PCR method, and the data were collated, plotted and analyzed. From 2016 to 2023, 12 779 cases of ILI and 9 166 cases of SARI were collected. The positive rate of HRSV was the highest in<5 years of age group [15.77% (168/1 065)], among which the positive rate was the highest in 2 to 5 years of age group of ILI cases [13.60% (31/228)], and the positive rate was the highest in 0 to 2 years of age group of SARI cases [25.97% (60/231)] (all values<0.001). The positive rate of HRSV in SARI cases was 2.31%-25.97%, higher than that in ILI cases (0-13.60%) (=0.016). HRSV was prevalent in autumn and winter from 2016 to 2020 and in spring in 2023. Alternating epidemics of HRSV virus type A and B in Hubei Province from 2016 to 2023 (dominant epidemics of type B in 2016 and 2020; dominant epidemics of type A in 2017-2019 and 2023). SARI and ILI patients under five years old are the main infection groups of HRSV. The seasonal prevalence characteristics of HRSV in Hubei Province from 2016 to 2023 shift from autumn and winter to spring.
分析2016年至2023年湖北省流感监测网络哨点医院急性呼吸道感染（ARIs）患者中人类呼吸道合胞病毒（HRSV）的流行病学特征。收集2016年至2023年湖北省流感监测哨点医院的ARIs样本[包括流感样病例（ILI）和严重急性呼吸道感染（SARI）]，并收集病例信息。采用荧光定量PCR法进行HRSV病毒核酸分型，对数据进行整理、绘图和分析。2016年至2023年，共收集12779例ILI病例和9166例SARI病例。HRSV阳性率在<5岁年龄组中最高[15.77%（168/1065）]，其中ILI病例中2至5岁年龄组阳性率最高[13.60%（31/228）]，SARI病例中0至2岁年龄组阳性率最高[25.97%（60/231）]（所有P值<0.001）。SARI病例中HRSV阳性率为2.31% - 25.97%，高于ILI病例（0 - 13.60%）（P = 0.016）。2016年至2020年HRSV在秋冬季节流行，2023年在春季流行。2016年至2023年湖北省HRSV A型和B型交替流行（2016年和2020年B型为主流；2017 - 2019年和2023年A型为主流）。5岁以下的SARI和ILI患者是HRSV的主要感染群体。2016年至2023年湖北省HRSV的季节性流行特征从秋冬转向春季。
