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依替膦酸对乳牙的抗菌效果评估:一项体外研究。

Evaluation of Antimicrobial Efficacy of Etidronic Acid against in Primary Teeth: An Study.

作者信息

Supraja Atluri N, Arali Veena, Rapala Harika, Vemagiri Charan T, Kallakuri Mounika, Kumar Gannamani Lgs P

机构信息

Department of Pediatric and Preventive Dentistry, Malla Reddy Institute of Dental Sciences (MRIDS), Hyderabad, Telangana, India.

Department of Pediatric and Preventive Dentistry, Vinayaka Mission's Sankarachariyar Dental College, Ariyanur, Salem, Tamil Nadu, India.

出版信息

Int J Clin Pediatr Dent. 2024 Apr;17(4):433-436. doi: 10.5005/jp-journals-10005-2834.

DOI:10.5005/jp-journals-10005-2834
PMID:39144173
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11320814/
Abstract

BACKGROUND

In pulpectomy, to remove the inflamed or diseased pulp tissues and smear layer, the root canal is disinfected with mechanical instrumentation and copious irrigation.

AIM

The purpose of this present study is to evaluate the antibacterial efficacy of etidronic acid as an irrigant in primary teeth.

MATERIALS AND METHODS

A total of 60 necrotic primary teeth in children aged 3-8 years were included. Of these, 30 were irrigated with 2% chlorhexidine (CHX) gluconate (group I) and 30 with 9% etidronic acid (group II). Two microbiological samples were collected with sterile paper points from the canal in both groups during the pulpectomy process-first after access opening and before the first irrigation (S1), and second after instrumentation and final irrigation, before filling (S2). The presence of was determined using colony-forming units per milliliter (CFU/mL) in all samples (S1 and S2).

RESULTS

After analyzing the samples before and after irrigation in groups I and II, there was a statistically significant reduction in CFU/mL ( < 0.05). Group II had a statistically significant advantage when the two groups were compared after irrigation.

CONCLUSION

As a result, etidronic acid can be recommended as a pulpectomy irrigating solution for necrotic primary teeth.

HOW TO CITE THIS ARTICLE

Supraja AN, Arali V, Rapala H, Evaluation of Antimicrobial Efficacy of Etidronic Acid against in Primary Teeth: An Study. Int J Clin Pediatr Dent 2024;17(4):433-436.

摘要

背景

在牙髓摘除术中,为去除发炎或患病的牙髓组织及玷污层,需通过机械预备和大量冲洗对根管进行消毒。

目的

本研究旨在评估依替膦酸作为乳牙冲洗液的抗菌效果。

材料与方法

纳入3 - 8岁儿童的60颗坏死乳牙。其中,30颗用2%葡萄糖酸氯己定(CHX)冲洗(I组),30颗用9%依替膦酸冲洗(II组)。在牙髓摘除过程中,两组均用无菌纸尖从根管采集两份微生物样本——一份在开髓后首次冲洗前(S1),另一份在预备和最终冲洗后、充填前(S2)。所有样本(S1和S2)均采用每毫升菌落形成单位(CFU/mL)来确定细菌的存在情况。

结果

分析I组和II组冲洗前后的样本后发现,CFU/mL有统计学显著降低(P < 0.05)。冲洗后两组比较时,II组具有统计学显著优势。

结论

因此,依替膦酸可推荐作为坏死乳牙牙髓摘除术的冲洗液。

如何引用本文

Supraja AN, Arali V, Rapala H, 依替膦酸对乳牙中[细菌名称未给出]抗菌效果的评估:一项[研究类型未给出]研究。《国际临床儿科牙科学杂志》2024;17(4):433 - 436。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/64f5/11320814/656595215bff/ijcpd-17-4-433-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/64f5/11320814/fba4323f51db/ijcpd-17-4-433-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/64f5/11320814/a65484421eb1/ijcpd-17-4-433-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/64f5/11320814/fd3202311aa5/ijcpd-17-4-433-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/64f5/11320814/656595215bff/ijcpd-17-4-433-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/64f5/11320814/fba4323f51db/ijcpd-17-4-433-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/64f5/11320814/a65484421eb1/ijcpd-17-4-433-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/64f5/11320814/fd3202311aa5/ijcpd-17-4-433-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/64f5/11320814/656595215bff/ijcpd-17-4-433-g004.jpg

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