Nordenström Simon, Lebedev Victor, Hartwig Stefan, Kruse Marlen, Marquetand Justus, Broser Philip, Middelmann Thomas
Physikalisch-Technische Bundesanstalt, 10587, Berlin, Germany.
Hertie Institute for Clinical Brain Research, University of Tübingen, 72076, Tübingen, Germany.
Sci Rep. 2024 Aug 16;14(1):18960. doi: 10.1038/s41598-024-69829-y.
While magnetomyography (MMG) using optically pumped magnetometers (OPMs) is a promising method for non-invasive investigation of the neuromuscular system, it has almost exclusively been performed in magnetically shielded rooms (MSRs) to date. MSRs provide extraordinary conditions for biomagnetic measurements but limit the widespread adoption of measurement methods due to high costs and extensive infrastructure. In this work, we address this issue by exploring the feasibility of mobile OPM-MMG in a setup of commercially available components. From field mapping and simulations, we find that the employed zero-field OPM can operate within a large region of the mobile shield, beyond which residual magnetic fields and perturbations become increasingly intolerable. Moreover, with digital filtering and moderate averaging a signal quality comparable to that in a heavily shielded MSR is attained. These findings facilitate practical and cost-effective implementations of OPM-MMG systems in clinical practice and research.
虽然使用光泵磁力仪（OPM）的磁肌电图（MMG）是一种用于非侵入性研究神经肌肉系统的有前景的方法，但迄今为止，它几乎完全是在磁屏蔽室（MSR）中进行的。磁屏蔽室为生物磁测量提供了绝佳条件，但由于成本高昂和基础设施庞大，限制了测量方法的广泛应用。在这项工作中，我们通过探索在商用组件设置中使用移动OPM-MMG的可行性来解决这个问题。通过场映射和模拟，我们发现所采用的零场OPM可以在移动屏蔽的大区域内运行，超过该区域，残余磁场和扰动变得越来越难以容忍。此外，通过数字滤波和适度平均，可以获得与在 heavily shielded MSR 中相当的信号质量。这些发现促进了OPM-MMG系统在临床实践和研究中的实际且经济高效的实施。
