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1
(Saffron): A potential multifunctional therapeutic agent for neurodegenerative disorders.（藏红花）：一种用于神经退行性疾病的潜在多功能治疗剂。
J Biomed Res. 2024 Aug 16;39(1):114-116. doi: 10.7555/JBR.38.20240131.
2
Possible therapeutic effects of stigma and its petal flavonoid, kaempferol, on respiratory disorders.菥蓂及其花瓣类黄酮（山奈酚）治疗呼吸系统疾病的潜在疗效。
Pharm Biol. 2020 Dec;58(1):1140-1149. doi: 10.1080/13880209.2020.1844762.
3
The therapeutic potential of Crocus sativus Linn.: A comprehensive narrative review of clinical trials.番红花属植物的治疗潜力：临床试验的综合叙述性评价。
Phytother Res. 2022 Jan;36(1):98-111. doi: 10.1002/ptr.7286. Epub 2021 Sep 17.
4
Crocus sativus a natural food coloring and flavoring has potent anti-tumor properties.番红花，一种天然的食用色素和香料，具有很强的抗肿瘤特性。
Phytomedicine. 2018 Apr 1;43:21-27. doi: 10.1016/j.phymed.2018.03.041. Epub 2018 Mar 19.
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Phytochemistry, quality control and medicinal uses of Saffron (.): an updated review.藏红花（.: 的植物化学、质量控制和药用用途：更新的综述。
J Med Life. 2023 Jun;16(6):822-836. doi: 10.25122/jml-2022-0353.
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Saffron (Crocus sativus L.) extract attenuates chronic scopolamine-induced cognitive impairment, amyloid beta, and neurofibrillary tangles accumulation in rats.藏红花（Crocus sativus L.）提取物可减轻慢性东莨菪碱诱导的大鼠认知障碍、β-淀粉样蛋白和神经原纤维缠结的积累。
J Ethnopharmacol. 2024 May 23;326:117898. doi: 10.1016/j.jep.2024.117898. Epub 2024 Feb 8.
7
Beneficial effects of saffron ( L.) in ocular pathologies, particularly neurodegenerative retinal diseases.藏红花（L.）在眼部疾病，尤其是神经退行性视网膜疾病中的有益作用。
Neural Regen Res. 2020 Aug;15(8):1408-1416. doi: 10.4103/1673-5374.274325.
8
Adding color to a century-old enigma: multi-color chromosome identification unravels the autotriploid nature of saffron (Crocus sativus) as a hybrid of wild Crocus cartwrightianus cytotypes.为一个百年之谜增添色彩：多色染色体鉴定揭示藏红花（Crocus sativus）作为野生卡特兰型 Crocus cartwrightianus 细胞型杂种的同源三倍体性质。
New Phytol. 2019 Jun;222(4):1965-1980. doi: 10.1111/nph.15715. Epub 2019 Mar 1.
9
Active constituents of saffron ( L.) and their prospects in treating neurodegenerative diseases (Review).藏红花的活性成分及其在治疗神经退行性疾病中的前景（综述）
Exp Ther Med. 2023 Apr 3;25(5):235. doi: 10.3892/etm.2023.11934. eCollection 2023 May.
10
Saffron ( L.): A Source of Nutrients for Health and for the Treatment of Neuropsychiatric and Age-Related Diseases.藏红花（L.）：一种营养来源，可促进健康并治疗神经精神和与年龄相关的疾病。
Nutrients. 2022 Jan 29;14(3):597. doi: 10.3390/nu14030597.

本文引用的文献

1
Effect of saffron supplementation on oxidative stress markers (MDA, TAC, TOS, GPx, SOD, and pro-oxidant/antioxidant balance): An updated systematic review and meta-analysis of randomized placebo-controlled trials.藏红花补充剂对氧化应激标志物（丙二醛、总抗氧化能力、总氧化状态、谷胱甘肽过氧化物酶、超氧化物歧化酶以及促氧化剂/抗氧化剂平衡）的影响：随机安慰剂对照试验的最新系统评价与荟萃分析
Front Med (Lausanne). 2023 Feb 1;10:1071514. doi: 10.3389/fmed.2023.1071514. eCollection 2023.
2
Saffron against Neuro-Cognitive Disorders: An Overview of Its Main Bioactive Compounds, Their Metabolic Fate and Potential Mechanisms of Neurological Protection.藏红花与神经认知障碍：其主要生物活性化合物概述、代谢命运及其潜在神经保护机制。
Nutrients. 2022 Dec 17;14(24):5368. doi: 10.3390/nu14245368.
3
The Pharmacological Activities of L.: A Review Based on the Mechanisms and Therapeutic Opportunities of its Phytoconstituents.《基于其植物化学成分的作用机制和治疗机会的研究进展：白头翁的药理学活性综述》。
Oxid Med Cell Longev. 2022 Feb 14;2022:8214821. doi: 10.1155/2022/8214821. eCollection 2022.
4
Effect of saffron supplementation on oxidative stress parameters: A systematic review and meta-analysis of randomized placebo-controlled trials.藏红花补充剂对氧化应激参数的影响：随机安慰剂对照试验的系统评价和荟萃分析
Food Sci Nutr. 2021 Aug 5;9(10):5809-5819. doi: 10.1002/fsn3.2463. eCollection 2021 Oct.
5
A qualitative and quantitative comparison of Crocus sativus and Nigella sativa immunomodulatory effects.番红花和黑种草籽免疫调节作用的定性和定量比较。
Biomed Pharmacother. 2021 Aug;140:111774. doi: 10.1016/j.biopha.2021.111774. Epub 2021 May 29.
6
Effects of Saffron Extract Supplementation on Mood, Well-Being, and Response to a Psychosocial Stressor in Healthy Adults: A Randomized, Double-Blind, Parallel Group, Clinical Trial.藏红花提取物补充剂对健康成年人情绪、幸福感及心理社会应激源反应的影响：一项随机、双盲、平行组临床试验
Front Nutr. 2021 Feb 1;7:606124. doi: 10.3389/fnut.2020.606124. eCollection 2020.
7
Saffron: Chemical Composition and Neuroprotective Activity.藏红花：化学成分和神经保护活性。
Molecules. 2020 Nov 29;25(23):5618. doi: 10.3390/molecules25235618.
8
Saffron for mild cognitive impairment and dementia: a systematic review and meta-analysis of randomised clinical trials.藏红花治疗轻度认知障碍和痴呆症的系统评价和荟萃分析：随机临床试验。
BMC Complement Med Ther. 2020 Nov 9;20(1):333. doi: 10.1186/s12906-020-03102-3.
9
Targeting Transcription Factor Nrf2 (Nuclear Factor Erythroid 2-Related Factor 2) for the Intervention of Vascular Cognitive Impairment and Dementia.针对转录因子 Nrf2（红细胞生成素相关因子 2）干预血管性认知障碍和痴呆。
Arterioscler Thromb Vasc Biol. 2021 Jan;41(1):97-116. doi: 10.1161/ATVBAHA.120.314804. Epub 2020 Oct 15.
10
Nuclear Factor-Erythroid 2-Related Factor 2 (Nrf2) and Mitochondrial Dynamics/Mitophagy in Neurological Diseases.核因子红细胞2相关因子2（Nrf2）与神经疾病中的线粒体动力学/线粒体自噬
Antioxidants (Basel). 2020 Jul 15;9(7):617. doi: 10.3390/antiox9070617.

(Saffron): A potential multifunctional therapeutic agent for neurodegenerative disorders.

作者信息

Khazdair M R

机构信息

Pharmaceutical Science and Clinical Physiology, Cardiovascular Diseases Research Center, Birjand University of Medical Sciences, Birjand 9717853111, Iran.

出版信息

J Biomed Res. 2024 Aug 16;39(1):114-116. doi: 10.7555/JBR.38.20240131.

DOI:10.7555/JBR.38.20240131
PMID:39148255
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11873588/
Abstract
摘要