Jin Jian, Li Shujuan, Huang Hehuan, Li Junqi, Lyu Yuan, Ran Yunwei, Chang Hui, Zhao Xin
Medical Research Center, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450002, P.R. China.
Institute of Neuroscience, Zhengzhou University, Zhengzhou, Henan 450002, P.R. China.
Exp Ther Med. 2024 Jul 31;28(4):382. doi: 10.3892/etm.2024.12671. eCollection 2024 Oct.
Human papillomavirus (HPV) infection plays an important role in cervical cancer. HPV is classified within the family and is a non-enveloped, small DNA virus. HPV infection can be classified into two distinct scenarios: i) With or without integration into the host chromosomes. Detection of its infection can be useful in the study of cervical lesions. In the present review, the structural and functional features of HPV, HPV typing, infection and transmission mode, the risk factors for cervical susceptibility to infection and HPV detection methods are described in detail. The development of HPV detection methods may have far-reaching significance in the prevention and treatment of cervical disease. This review summarizes the advantages and limitations of each HPV detection method.
人乳头瘤病毒（HPV）感染在宫颈癌中起着重要作用。HPV属于乳头瘤病毒科，是一种无包膜的小型DNA病毒。HPV感染可分为两种不同情况：i）整合或未整合到宿主染色体中。检测其感染情况对宫颈病变的研究有帮助。在本综述中，详细描述了HPV的结构和功能特征、HPV分型、感染和传播方式、宫颈易感染的危险因素以及HPV检测方法。HPV检测方法的发展可能对宫颈疾病的防治具有深远意义。本综述总结了每种HPV检测方法的优缺点。
