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From hearing loss to neurological complications: Is there an "ear glymphatic system"?

作者信息

Bi Yanlin, Yang Yunchao, Zhang Gaofeng, Wang Hong, Dong Rui

机构信息

Department of Anesthesiology, Qingdao Municipal Hospital (Qingdao Hospital, University of Health and Rehabilitation Sciences), Qingdao, China.

Department of Pediatrics, Qingdao Women and Children's Hospital, Qingdao University, Qingdao, China.

出版信息

CNS Neurosci Ther. 2024 Aug;30(8):e14846. doi: 10.1111/cns.14846.

DOI:10.1111/cns.14846
PMID:39169514
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11338835/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6bb7/11338835/1da9075476ed/CNS-30-e14846-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6bb7/11338835/1da9075476ed/CNS-30-e14846-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6bb7/11338835/1da9075476ed/CNS-30-e14846-g001.jpg

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本文引用的文献

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Association between severe preoperative hearing impairment and postoperative emergence agitation among elderly patients undergoing middle ear surgery.中耳手术老年患者术前重度听力障碍与术后苏醒期躁动的相关性。
J Clin Anesth. 2023 Dec;91:111254. doi: 10.1016/j.jclinane.2023.111254. Epub 2023 Sep 8.
2
Evaluation of glymphatic system activity by diffusion tensor image analysis along the perivascular space in presbycusis.评估 presbycusis 时沿血管周围间隙的扩散张量图像分析的糖液系统活动。
CNS Neurosci Ther. 2024 Mar;30(3):e14458. doi: 10.1111/cns.14458. Epub 2023 Sep 8.
3
Delivery of gene therapy through a cerebrospinal fluid conduit to rescue hearing in adult mice.
通过脑脊液导管递送基因治疗以挽救成年小鼠的听力。
Sci Transl Med. 2023 Jun 28;15(702):eabq3916. doi: 10.1126/scitranslmed.abq3916.
4
The Glymphatic System in Humans: Investigations With Magnetic Resonance Imaging.人体中的类淋巴系统:磁共振成像研究
Invest Radiol. 2024 Jan 1;59(1):1-12. doi: 10.1097/RLI.0000000000000969. Epub 2023 Mar 13.
5
Hearing impairment is associated with cognitive decline, brain atrophy and tau pathology.听力损伤与认知能力下降、脑萎缩和 tau 病理学有关。
EBioMedicine. 2022 Dec;86:104336. doi: 10.1016/j.ebiom.2022.104336. Epub 2022 Nov 7.
6
Association of MRI Indices of Glymphatic System With Amyloid Deposition and Cognition in Mild Cognitive Impairment and Alzheimer Disease.MRI 指数与轻度认知障碍和阿尔茨海默病中淀粉样蛋白沉积及认知的相关性研究。
Neurology. 2022 Dec 12;99(24):e2648-e2660. doi: 10.1212/WNL.0000000000201300.
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Worsening hearing was associated with higher β-amyloid and tau burden in age-related hearing loss.与年龄相关性听力损失相关的听力恶化与较高的β-淀粉样蛋白和tau 负担有关。
Sci Rep. 2022 Jun 21;12(1):10493. doi: 10.1038/s41598-022-14466-6.
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Sci Transl Med. 2020 Mar 25;12(536). doi: 10.1126/scitranslmed.aaw3210.
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