School of Pharmacy, Faculty of Medical & Health Sciences, University of Auckland, Auckland, New Zealand.
School of Pharmacy, University of Queensland, Brisbane, Australia.
J Med Syst. 2024 Aug 23;48(1):79. doi: 10.1007/s10916-024-02097-5.
The purpose of this scoping review is to identify and evaluate studies that examine the effectiveness and implementation strategies of Electronic Health Record (EHR)-integrated digital technologies aimed at improving medication-related outcomes and promoting health equity among hospitalised adults. Using the Consolidated Framework for Implementation Research (CFIR), the implementation methods and outcomes of the studies were evaluated, as was the assessment of methodological quality and risk of bias. Searches through Medline, Embase, Web of Science, and CINAHL Plus yielded 23 relevant studies from 1,232 abstracts, spanning 11 countries and from 2008 to 2022, with varied research designs. Integrated digital tools such as alert systems, clinical decision support systems, predictive analytics, risk assessment, and real-time screening and surveillance within EHRs demonstrated potential in reducing medication errors, adverse events, and inappropriate medication use, particularly in older patients. Challenges include alert fatigue, clinician acceptance, workflow integration, cost, data integrity, interoperability, and the potential for algorithmic bias, with a call for long-term and ongoing monitoring of patient safety and health equity outcomes. This review, guided by the CFIR framework, highlights the importance of designing health technology based on evidence and user-centred practices. Quality assessments identified eligibility and representativeness issues that affected the reliability and generalisability of the findings. This review also highlights a critical research gap on whether EHR-integrated digital tools can address or worsen health inequities among hospitalised patients. Recognising the growing role of Artificial Intelligence (AI) and Machine Learning (ML), this review calls for further research on its influence on medication management and health equity through integration of EHR and digital technology.
本范围综述的目的是识别和评估旨在改善住院成人药物相关结局和促进健康公平的电子健康记录(EHR)集成数字技术的有效性和实施策略的研究。使用实施研究综合框架(CFIR),评估了研究的实施方法和结果,以及方法学质量和偏倚风险评估。通过 Medline、Embase、Web of Science 和 CINAHL Plus 进行搜索,从 1232 篇摘要中筛选出 23 项相关研究,这些研究来自 11 个国家,跨越 2008 年至 2022 年,研究设计各不相同。EHR 中的警报系统、临床决策支持系统、预测分析、风险评估和实时筛查和监测等集成数字工具在减少药物错误、不良事件和不适当用药方面具有潜力,尤其是在老年患者中。挑战包括警报疲劳、临床医生接受度、工作流程整合、成本、数据完整性、互操作性和算法偏差的潜在风险,需要对患者安全和健康公平结果进行长期和持续监测。本综述以 CFIR 框架为指导,强调了基于证据和以用户为中心的实践设计健康技术的重要性。质量评估确定了影响研究结果可靠性和普遍性的资格和代表性问题。本综述还强调了一个关键的研究空白,即 EHR 集成数字工具是否可以解决或加剧住院患者的健康不公平问题。认识到人工智能(AI)和机器学习(ML)的作用日益增强,本综述呼吁进一步研究其通过 EHR 和数字技术的整合对药物管理和健康公平的影响。