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埃塞俄比亚南部西古吉州布勒霍拉血库供血者中输血传播感染的流行情况及趋势评估

Evaluation of Transfusion Transmissible Infections Prevalence and Trend Among Blood Donors Attended at Bule Hora Blood Bank, West Guji, South Ethiopia.

作者信息

Aliyo Alqeer, Ashenafi Girma, Adem Seid

机构信息

Medical Laboratory Science Department, Institute of Health, Bule Hora University, Bule Hora, Ethiopia.

出版信息

Health Serv Res Manag Epidemiol. 2022 Nov 3;9:23333928221136717. doi: 10.1177/23333928221136717. eCollection 2022 Jan-Dec.

Abstract

BACKGROUND

Transfusion transmissible infections (TTIs) are among the greatest threats to blood safety for recipients and the economy of the developed and developing countries. Therefore, the study of the prevalence and trends of TTIs is important to assess for its prevention and control strategies.

OBJECTIVES

This study aimed to evaluate the prevalence and trend of transfusion transmissible infections among blood donors at the Bule Hora Blood Bank, West Guji, Ethiopia, from 2019 to 2021.

METHOD

A retrospective study was conducted on all blood donors at the Bule Hora Blood Bank from 2019-2021. The data of 4193 blood donors were collected from the databank (logbook) of the blood bank using a checklist. Data were analyzed by using SPSS software, and the chi-square test was used to assess the association between independent variables and transfusion transmission infection. Different types of graphs, charts and tables were used to present the data. P values less than .05 were considered statistically significant.

RESULT

The overall transfusion transmissible infection among blood donors was 4.6% (192). Out of the tested blood donors, 86 (2.1%) were found to be seropositive for hepatitis B virus. The trend analysis showed that the positivity rates of the screened tests were 28 (4.72%) in 2019, decreased to 77 (4.26%) in 2020 and increased to 87 (4.86%) in 2021. The sex of blood donors was significantly associated with TTIs ( value = .021), and the positivity rates were significantly higher among male than female blood donors. The study results showed that overall seropositivity rates increased along the age groups of the donors.

CONCLUSION

The study reported a moderate prevalence of transfusion transmissible infections among blood donors visiting the Bule hora blood bank. Health education about the transmission, prevention and create awareness of TTIs should be strengthened by the government and non-government organization.

摘要

背景

输血传播感染(TTIs)是发达国家和发展中国家受血者血液安全及经济面临的最大威胁之一。因此,研究输血传播感染的流行情况和趋势对于评估其预防和控制策略至关重要。

目的

本研究旨在评估2019年至2021年埃塞俄比亚西古吉州布勒霍拉血库献血者中输血传播感染的流行情况和趋势。

方法

对布勒霍拉血库2019 - 2021年的所有献血者进行回顾性研究。使用清单从血库数据库(日志)中收集4193名献血者的数据。采用SPSS软件进行数据分析,卡方检验用于评估自变量与输血传播感染之间的关联。使用不同类型的图表和表格呈现数据。P值小于0.05被认为具有统计学意义。

结果

献血者中输血传播感染的总体发生率为4.6%(192例)。在接受检测的献血者中,86例(2.1%)乙型肝炎病毒血清学检测呈阳性。趋势分析表明,筛查检测的阳性率在2019年为28例(4.72%),2020年降至77例(4.26%),2021年增至87例(4.86%)。献血者的性别与输血传播感染显著相关(P值 = 0.021),男性献血者的阳性率显著高于女性献血者。研究结果显示,总体血清阳性率随献血者年龄组增加而上升。

结论

该研究报告称,前往布勒霍拉血库的献血者中输血传播感染的流行程度为中等。政府和非政府组织应加强关于输血传播感染的传播、预防及提高认识的健康教育。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d6d8/9634199/2074981e2c58/10.1177_23333928221136717-fig1.jpg

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