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Structural basis for inhibition of the cardiac sodium channel by the atypical antiarrhythmic drug ranolazine.

作者信息

Lenaeus Michael, Gamal El-Din Tamer M, Tonggu Lige, Zheng Ning, Catterall William A

机构信息

Division of General Internal Medicine, Department of Medicine, University of Washington, Seattle, WA, USA.

Department of Pharmacology, University of Washington, Seattle, WA, USA.

出版信息

Nat Cardiovasc Res. 2023 Jun;2(6):587-594. doi: 10.1038/s44161-023-00271-5. Epub 2023 May 4.

DOI:10.1038/s44161-023-00271-5
PMID:39185478
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11343317/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4ed/11343317/439c12184673/nihms-1984459-f0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4ed/11343317/cb4a5418479f/nihms-1984459-f0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4ed/11343317/38100202e852/nihms-1984459-f0006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4ed/11343317/f9c086bd4da1/nihms-1984459-f0007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4ed/11343317/b3a42aeda994/nihms-1984459-f0008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4ed/11343317/9b44747fd57f/nihms-1984459-f0009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4ed/11343317/631676da6b3d/nihms-1984459-f0010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4ed/11343317/6c65c91e86e6/nihms-1984459-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4ed/11343317/cc9333ebfc59/nihms-1984459-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4ed/11343317/ef74bab845b9/nihms-1984459-f0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4ed/11343317/439c12184673/nihms-1984459-f0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4ed/11343317/cb4a5418479f/nihms-1984459-f0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4ed/11343317/38100202e852/nihms-1984459-f0006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4ed/11343317/f9c086bd4da1/nihms-1984459-f0007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4ed/11343317/b3a42aeda994/nihms-1984459-f0008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4ed/11343317/9b44747fd57f/nihms-1984459-f0009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4ed/11343317/631676da6b3d/nihms-1984459-f0010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4ed/11343317/6c65c91e86e6/nihms-1984459-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4ed/11343317/cc9333ebfc59/nihms-1984459-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4ed/11343317/ef74bab845b9/nihms-1984459-f0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4ed/11343317/439c12184673/nihms-1984459-f0004.jpg

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