Emergence of in pediatrics: Molecular insights from a hospital in East China.

is a novel species within the complex and can cause serious bloodstream infections (BSIs) in humans, which have been mainly reported in adults, especially the elderly. In this study, we analyzed the molecular characterization of a strain of (22WJ8192) isolated from the peripheral vein blood sample of a seven-month-old female infant in Eastern China. The 22WJ8192 belonged to sequence type (ST)2250 and harbored six antibiotic-resistance genes and 53 virulence genes and was resistant to penicillin. Additionally, we conducted a comparative analysis of the molecular characteristics of sourced from various origins within the dataset, predominantly from the National Center for Biotechnology Information Collection (NCBI) genome database. Antibiotic-resistance genes , , , , , , , and were more prevalent among the strains of human origin. Virulence genes , , , , , and were more prevalent among strains of human origin. The presence of antibiotic-resistance genes , , , , and in strain 22WJ8192 was also more common among strains of human origin in the dataset. Conversely, the antibiotic-resistance genes , , and , typically found in strains of human origin, were not detected in 22WJ8192. Additionally, virulence genes , , , , , and present in 22WJ8192 exhibited a higher prevalence among strains of human origin in the dataset. In conclusion, this study emphasizes the potential of ST2250 to induce severe bloodstream infections in infants, shedding light on the molecular characteristics of this strain.