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针对慢性肾脏病患者饮食钠摄入的生活方式改变的有效方法:FROM-J 研究的亚分析。

Effective method for life-style modifications focused on dietary sodium intake in chronic kidney disease: sub-analysis of the FROM-J study.

机构信息

Comprehensive Human Sciences Doctoral Program in Medical Sciences, University of Tsukuba, Tsukuba, Japan.

Tohto University, Chiba, Japan.

出版信息

BMC Nephrol. 2024 Aug 26;25(1):274. doi: 10.1186/s12882-024-03707-7.

DOI:10.1186/s12882-024-03707-7
PMID:39187778
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11348764/
Abstract

BACKGROUND

Lifestyle modifications by educational sessions are an important component of multidisciplinary treatment for chronic kidney disease (CKD). We attempted to identify the best method to teach these modifications in order to ensure their acceptance by patients and investigated its effectiveness in CKD practice.

METHODS

This study is a post-hoc analysis of the FROM-J study. Subjects were 876 CKD patients in the advanced care group of the FROM-J study who had received lifestyle modification sessions every 3 months for 3.5 years. Two-hundred and ten males (32.6%) and 89 females (38.2%) showed success in sodium restriction. In this study, we examined factors affecting sodium restriction in these subjects.

RESULTS

Subjects received three or more consecutive educational sessions about improvement of salt intake. The median salt-intake improvement maintenance period was 407 days. The number of dietary counseling sessions (OR 1.090, 95%CI: 1.012-1.174) in males and the number of dietary counseling sessions (OR 1.159, 95%CI: 1.019-1.318), CKD stage progression (OR 1.658, 95%CI: 1.177-2.335), and collaboration with a nephrologist (OR 2.060, 95%CI: 1.073-3.956) in females were identified as significant factors improving salt intake. The only factor contributing to the maintenance of improved salt intake was the continuation of dietary counseling (p = 0.013).

CONCLUSION

An increased number of educational sessions was the only successful approach for males to implement and maintain an improved salt intake. Providing the resources for continuous counseling is beneficial for lifestyle modifications and their maintenance in the long-term management of CKD. Continuous counseling for lifestyle modifications is highly cost-effective.

TRIAL REGISTRATION

The FROM-J study was registered in UMIN000001159 on 16/05/2008.

摘要

背景

通过教育课程进行生活方式的改变是慢性肾脏病(CKD)多学科治疗的重要组成部分。我们试图确定教授这些改变的最佳方法,以确保患者接受它们,并研究其在 CKD 实践中的有效性。

方法

这是 FROM-J 研究的事后分析。FROM-J 研究的高级护理组中的 876 名 CKD 患者每 3 个月接受一次生活方式改变课程,为期 3.5 年。210 名男性(32.6%)和 89 名女性(38.2%)成功限制了钠的摄入。在这项研究中,我们检查了影响这些患者限制钠摄入的因素。

结果

受试者接受了 3 次或更多次连续的关于改善盐摄入量的教育课程。盐摄入量改善维持期的中位数为 407 天。男性的饮食咨询次数(OR 1.090,95%CI:1.012-1.174)和饮食咨询次数(OR 1.159,95%CI:1.019-1.318)、CKD 阶段进展(OR 1.658,95%CI:1.177-2.335)以及与肾病医生合作(OR 2.060,95%CI:1.073-3.956)是改善盐摄入量的显著因素。唯一有助于维持改善后的盐摄入量的因素是继续进行饮食咨询(p=0.013)。

结论

增加教育课程的次数是男性实施和维持盐摄入量改善的唯一成功方法。提供持续咨询的资源有利于 CKD 长期管理中的生活方式改变及其维持。生活方式改变的持续咨询具有很高的成本效益。

试验注册

FROM-J 研究于 2008 年 5 月 16 日在 UMIN000001159 上注册。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a28/11348764/516480aa9198/12882_2024_3707_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a28/11348764/516480aa9198/12882_2024_3707_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a28/11348764/516480aa9198/12882_2024_3707_Fig1_HTML.jpg

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本文引用的文献

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Trends in the incidence of kidney replacement therapy: comparisons of ERA, USRDS and Japan registries.肾脏替代治疗的发病率趋势:欧洲肾脏协会注册研究(ERA)、美国肾脏数据系统(USRDS)和日本注册研究的比较
Nephrol Dial Transplant. 2023 Mar 31;38(4):797-799. doi: 10.1093/ndt/gfac312.
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Increasing numbers and improved overall survival of patients on kidney replacement therapy over the last decade in Europe: an ERA Registry study.在过去十年中,在欧洲接受肾脏替代治疗的患者数量不断增加,整体生存率也得到了提高:一项 ERA 登记研究。
Nephrol Dial Transplant. 2023 Mar 31;38(4):1027-1040. doi: 10.1093/ndt/gfac165.
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Long-term effectiveness of a primary care practice facilitation program for chronic kidney disease management: an extended follow-up of a cluster-randomized FROM-J study.
基层医疗实践促进计划对慢性肾脏病管理的长期效果:FROM-J 研究的扩展随访。
Nephrol Dial Transplant. 2023 Jan 23;38(1):158-166. doi: 10.1093/ndt/gfac041.
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Behaviour modification intervention for patients with chronic kidney disease could provide a mid- to long-term reduction in public health care expenditure: budget impact analysis.行为改变干预措施可降低慢性肾脏病患者的医疗费用:预算影响分析
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