Shao Changmin, Yu Yunru, Fan Qihui, Wang Xiaochen, Ye Fangfu
Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health) Wenzhou Institute University of Chinese Academy of Sciences Wenzhou Zhejiang China.
Beijing National Laboratory for Condensed Matter Physics Institute of Physics Chinese Academy of Sciences Beijing China.
Smart Med. 2022 Dec 23;1(1):e20220008. doi: 10.1002/SMMD.20220008. eCollection 2022 Dec.
The monitoring of mechanical indexes involved in body movement has attracted immense interest in the diagnosis of neurodegenerative diseases. Here, we present a hybrid flexible conductive structural color (SC) film with the capability of dual-signal mechanics screening. The film is constructed by oxidatively polymerizing pyrrole on the surface of an inverse opal polyurethane (IPU) membrane, which can be utilized to measure the mechanical indexes through resistance change. Owing to the inverse opal structure, the film shows visual structural color change when stretched and released according to the body movement. Additionally, the highly uniform ordered porous structure endows the conductive film with a lower coefficient of variance on relative resistance change. Benefiting from these features, we have demonstrated that such a flexible conductive SC film could monitor Parkinson's disease (PD) by detecting mechanical indexes simultaneously via dual signals. These features indicate the great value of the stretchable conductive SC films in mechanics sensing applications.
对身体运动所涉及的力学指标进行监测，在神经退行性疾病的诊断中引起了极大的关注。在此，我们展示了一种具有双信号力学筛选能力的混合柔性导电结构色（SC）薄膜。该薄膜是通过在反蛋白石聚氨酯（IPU）膜表面氧化聚合吡咯构建而成的，可用于通过电阻变化来测量力学指标。由于具有反蛋白石结构，该薄膜在根据身体运动拉伸和释放时会呈现出视觉上的结构色变化。此外，高度均匀有序的多孔结构使导电薄膜在相对电阻变化方面具有较低的变异系数。受益于这些特性，我们已经证明，这种柔性导电SC薄膜可以通过双信号同时检测力学指标来监测帕金森病（PD）。这些特性表明可拉伸导电SC薄膜在力学传感应用中具有巨大价值。
