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基于水凝胶的用于癌症检测的生物传感器的最新进展。

Recent Advances in Hydrogel-Based Biosensors for Cancer Detection.

机构信息

Department of Materials, Loughborough University, Loughborough LE11 3TU, United Kingdom.

出版信息

ACS Appl Mater Interfaces. 2024 Sep 11;16(36):46988-47002. doi: 10.1021/acsami.4c02317. Epub 2024 Aug 27.

DOI:10.1021/acsami.4c02317
PMID:39190320
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11403555/
Abstract

Early cancer detection is crucial for effective treatment, but current methods have limitations. Novel biomaterials, such as hydrogels, offer promising alternatives for developing biosensors for cancer detection. Hydrogels are three-dimensional and cross-linked networks of hydrophilic polymers that have properties similar to biological tissues. They can be combined with various biosensors to achieve high sensitivity, specificity, and stability. This review summarizes the recent advances in hydrogel-based biosensors for cancer detection, their synthesis, their applications, and their challenges. It also discusses the implications and future directions of this emerging field.

摘要

早期癌症检测对于有效治疗至关重要，但目前的方法存在局限性。新型生物材料，如水凝胶，为开发用于癌症检测的生物传感器提供了有前途的替代品。水凝胶是由亲水性聚合物交联形成的三维网络，具有类似于生物组织的特性。它们可以与各种生物传感器结合使用，以实现高灵敏度、特异性和稳定性。本文综述了水凝胶基生物传感器在癌症检测方面的最新进展，包括它们的合成、应用和面临的挑战。本文还讨论了这一新兴领域的意义和未来方向。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c5f9/11403555/d0079791f607/am4c02317_0006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c5f9/11403555/1c51c44e66cd/am4c02317_0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c5f9/11403555/c5de959ecb48/am4c02317_0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c5f9/11403555/3bf5c2e39c0c/am4c02317_0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c5f9/11403555/8a02d15497b0/am4c02317_0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c5f9/11403555/89dcdacaef48/am4c02317_0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c5f9/11403555/d0079791f607/am4c02317_0006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c5f9/11403555/1c51c44e66cd/am4c02317_0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c5f9/11403555/c5de959ecb48/am4c02317_0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c5f9/11403555/3bf5c2e39c0c/am4c02317_0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c5f9/11403555/8a02d15497b0/am4c02317_0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c5f9/11403555/89dcdacaef48/am4c02317_0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c5f9/11403555/d0079791f607/am4c02317_0006.jpg

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