Khan Muzamil, Shah Kinjal, Gill Satkarjeet Kaur, Gul Nida, J Jestin K, Valladares Vivian, Khan Laiba Ali, Raza Muhammad
Internal Medicine, George Washington University School of Medicine and Health Sciences, Washington, DC, USA.
Health Administration, Edward J. Bloustein School of Planning and Public Policy, New Jersey, USA.
Cureus. 2024 Jul 27;16(7):e65552. doi: 10.7759/cureus.65552. eCollection 2024 Jul.
Introduction Gastroesophageal reflux disease (GERD) is marked by the frequent occurrence of stomach acid flowing back into the esophagus, causing symptoms such as heartburn and acid regurgitation at least once a week. When reflux leads to troublesome symptoms and esophageal damage and adversely affects quality of life, it is diagnosed as GERD. Age, gender, ethnicity, genetic predispositions, and aspects of diet and lifestyle, including factors like obesity and smoking, are associated with GERD. Methodology This cross-sectional study was conducted within the Departments of General Medicine, Surgery, and Gastroenterology at Khyber Teaching Hospital (KTH) in Peshawar, spanning from January 2024 to June 2024. Patients who visited these departments or the Outpatient Department within the specified period with GERD were included in the study. A non-probability purposive sampling technique was used. For the analysis, we utilized IBM SPSS Statistics version 21. Results This study consists of 280 participants. The mean age of the participants in this study was 44.60 years. GERD has a significant association with obesity (69.99) and lack of exercise (80%), and a negative association was found between other gastrointestinal conditions (55.71%) and smoking (64.28). Common symptoms among GERD patients were swallowing difficulty, regurgitation, heartburn, and chest pain. Conclusion Our study is the first to examine the relationship between lifestyle factors and GERD among Pakistani patients. Our findings highlight significant associations between GERD and several factors, including gender, BMI, dietary habits, and lack of exercise. Notably, cultural and regional differences appear to influence GERD prevalence and its risk factors, as demonstrated by the minimal impact of alcohol consumption in our study population.
引言
胃食管反流病(GERD)的特征是胃酸频繁反流至食管,导致烧心和反酸等症状,每周至少出现一次。当反流导致令人困扰的症状和食管损伤,并对生活质量产生不利影响时,即可诊断为GERD。年龄、性别、种族、遗传易感性以及饮食和生活方式等方面,包括肥胖和吸烟等因素,都与GERD有关。
方法
本横断面研究于2024年1月至2024年6月在白沙瓦开伯尔教学医院(KTH)的普通内科、外科和胃肠病科进行。在指定期间到这些科室或门诊部就诊的GERD患者被纳入研究。采用了非概率目的抽样技术。分析时,我们使用了IBM SPSS Statistics 21版本。
结果
本研究共有280名参与者。本研究中参与者的平均年龄为44.60岁。GERD与肥胖(69.99%)和缺乏运动(80%)有显著关联,而其他胃肠道疾病(55.71%)和吸烟(64.28%)与之呈负相关。GERD患者的常见症状有吞咽困难、反流、烧心和胸痛。
结论
我们的研究首次探讨了巴基斯坦患者生活方式因素与GERD之间的关系。我们的研究结果突出了GERD与包括性别、体重指数、饮食习惯和缺乏运动在内的几个因素之间的显著关联。值得注意的是,文化和地区差异似乎会影响GERD的患病率及其危险因素,正如我们研究人群中饮酒影响极小所表明的那样。