Department of Clinical Sciences, School of Medicine, Imam Khomeini Hospital, Jiroft University of Medical Sciences, Jiroft, Iran.
Department of Internal Medicine, School of Medicine, Imam Khomeini Hospital, Jiroft University of Medical Sciences, Jiroft, Iran.
Arch Razi Inst. 2024 Feb 1;79(1):145-153. doi: 10.32592/ARI.2024.79.1.145. eCollection 2024 Feb.
The COVID-19 disease is a newly emerging disease, and the COVID-19 vaccine is one of the necessities to prevent this disease. The present study aimed to investigate the side effects of COVID-19 vaccines in southern Iran. We used convenience sampling to conduct this cross-sectional study on 647 people living in cities under coverage in Kerman province, southern Iran. The data collection tool was a researcher-made questionnaire of vaccine symptoms and signs. The results were analyzed using ANOVA and Chi-squared tests by SPSS software (version 24). The mean age of the participants was 40.19±15.20. The results indicated that 431 people (66.6%) reported post-vaccination side effects, with 18.23% of them having severe side effects. We noticed the most severe side effects in AstraZeneca, Sinopharm, Sputnik, and Bharat. Fever, headache, and pain at the injection site were the most common side effects after vaccination in descending order, which had a statistically significant relationship with all types of vaccines (=0.001). The side effects differed in the types of vaccines, and most of the vaccines had mild to moderate side effects. People with the B blood type showed the most severe side effects, while those with the AB showed the lowest rate of side effects. Therefore, the injection of the AstraZeneca vaccine in blood group B should be done with more caution. More attention should also be paid to blood groups B and A in the injection of COVID-19 vaccines. Moreover, health officials and the government should plan appropriate educational strategies to increase public awareness of the importance of vaccines in eradicating viral infections.
新型冠状病毒疾病是一种新出现的疾病，而新型冠状病毒疫苗是预防这种疾病的必要手段之一。本研究旨在调查伊朗南部新型冠状病毒疫苗的副作用。我们使用便利抽样法，对居住在伊朗南部克尔曼省覆盖城市的 647 人进行了这项横断面研究。数据收集工具是研究人员制作的疫苗症状和体征问卷。使用 SPSS 软件（版本 24）的 ANOVA 和卡方检验对结果进行分析。参与者的平均年龄为 40.19±15.20 岁。结果表明，有 431 人（66.6%）报告接种疫苗后出现副作用，其中 18.23%的人出现严重副作用。我们注意到阿斯利康、国药、卫星 V 和 Bharat 疫苗的副作用最严重。接种疫苗后最常见的副作用是发烧、头痛和注射部位疼痛，按降序排列，与所有类型的疫苗均呈统计学显著关系（=0.001）。疫苗类型不同，副作用也不同，大多数疫苗的副作用为轻度至中度。B 型血的人出现最严重的副作用，而 AB 型血的人出现副作用的比例最低。因此，在 B 型血人群中接种阿斯利康疫苗时应更加谨慎。在接种新型冠状病毒疫苗时，还应更加关注 B 型和 A 型血人群。此外，卫生官员和政府应制定适当的教育策略，提高公众对疫苗在消除病毒感染方面重要性的认识。
