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聚乙二醇4000对58S生物活性玻璃物理及微观结构性能的影响

The Influence of PEG 4000 on the Physical and Microstructural Properties of 58S Bioactive Glasses.

作者信息

Lixandru Matei Ioana Lavinia, Sava Bogdan Alexandru, Sarosi Codruta, Dușescu-Vasile Cristina, Popovici Daniela Roxana, Ionescu Andreea Iuliana, Bomboș Dorin, Băjan Marian, Doukeh Rami

机构信息

Botanical SRL, 7 Trandafirilor Street, 107059 Ploiești, Romania.

Faculty of Chemical Engineering and Biotechnologies, University Politehnica Bucharest-UPB, 313 Splaiul Independenței, 060042 Bucharest, Romania.

出版信息

Nanomaterials (Basel). 2024 Aug 6;14(16):1323. doi: 10.3390/nano14161323.

DOI:10.3390/nano14161323
PMID:39195362
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11357229/
Abstract

Bioactive glass is currently considered a material with a high biocompatibility and has been used both in the field of bone regeneration and in the preparation of cosmetic products with the controlled release of active compounds. The present work involved a study on the synthesis of bioglass using the sol-gel process. The study aims to evaluate the influence of the treatment of bioglass with Polyethylene glycol 4000 (PEG 4000) on its main characteristics. The surface characteristics of this material were obtained by nitrogen adsorption/desorption analysis, using the standard BET (Brunauer-Emmett-Teller) equation, the crystallinity by XRD (X-ray diffraction) analysis, the surface structure by SEM (Scanning Electron Microscope), thermal stability by TGA (ThermoGravimetric Analyses), and chemical bonds changes by FTIR (Fourier transform infrared) spectroscopy. After treatment with PEG 4000, the average diameter of the pores increased insignificantly, the crystallinity peak disappeared, and the SEM analysis highlighted several clusters of very small sizes.

摘要

生物活性玻璃目前被认为是一种具有高生物相容性的材料,已被用于骨再生领域以及用于制备具有活性化合物控释功能的化妆品。目前的工作涉及使用溶胶 - 凝胶法合成生物玻璃的研究。该研究旨在评估用聚乙二醇4000(PEG 4000)处理生物玻璃对其主要特性的影响。通过使用标准BET(布鲁诺尔 - 埃米特 - 特勒)方程的氮吸附/解吸分析获得该材料的表面特性,通过XRD(X射线衍射)分析获得结晶度,通过SEM(扫描电子显微镜)获得表面结构,通过TGA(热重分析)获得热稳定性,以及通过FTIR(傅里叶变换红外)光谱获得化学键变化。用PEG 4000处理后,孔隙的平均直径略有增加,结晶度峰消失,并且SEM分析突出显示了几个非常小尺寸的团簇。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f690/11357229/2d1e62a197a5/nanomaterials-14-01323-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f690/11357229/4dcfd88fdbe9/nanomaterials-14-01323-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f690/11357229/2e64bba9b031/nanomaterials-14-01323-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f690/11357229/016679f4d66d/nanomaterials-14-01323-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f690/11357229/9080b12a6132/nanomaterials-14-01323-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f690/11357229/37882d269638/nanomaterials-14-01323-g005a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f690/11357229/db1ae85b0e1c/nanomaterials-14-01323-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f690/11357229/46d34bfae3a4/nanomaterials-14-01323-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f690/11357229/cd820c0cf505/nanomaterials-14-01323-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f690/11357229/bbcecf87d8c0/nanomaterials-14-01323-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f690/11357229/2d1e62a197a5/nanomaterials-14-01323-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f690/11357229/4dcfd88fdbe9/nanomaterials-14-01323-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f690/11357229/2e64bba9b031/nanomaterials-14-01323-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f690/11357229/016679f4d66d/nanomaterials-14-01323-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f690/11357229/9080b12a6132/nanomaterials-14-01323-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f690/11357229/37882d269638/nanomaterials-14-01323-g005a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f690/11357229/db1ae85b0e1c/nanomaterials-14-01323-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f690/11357229/46d34bfae3a4/nanomaterials-14-01323-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f690/11357229/cd820c0cf505/nanomaterials-14-01323-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f690/11357229/bbcecf87d8c0/nanomaterials-14-01323-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f690/11357229/2d1e62a197a5/nanomaterials-14-01323-g010.jpg

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