Peitl Filho O, LaTorre G P, Hench L L
São Carlos Federal University, São Paulo, Brazil.
J Biomed Mater Res. 1996 Apr;30(4):509-14. doi: 10.1002/(SICI)1097-4636(199604)30:4<509::AID-JBM9>3.0.CO;2-T.
The bioactive glass 45S5 was crystallized to 8-100 vol % of crystals by thermal treatments from 550-680 degrees C. The micro-structure of the glass-ceramics had a very uniform crystal size, ranging from 8 to 20 microns. Fourier-transform infrared (FTIR) spectroscopy was used to determine the rate of hydroxycarbonate apatite (HCA) formation that occurs on bioactive glass and glass-ceramic implants when exposed to simulated body fluid (SBF) solutions. Crystallization did not inhibit development of a crystalline HCA layer, but the onset time of crystallization increased from 10 h for the parent glass to 22 h for 100% crystallized glass-ceramic. The rate of surface reactions was slower when the percentage of crystallization was > or = 60%.
生物活性玻璃45S5通过550 - 680摄氏度的热处理结晶为8 - 100体积%的晶体。玻璃陶瓷的微观结构具有非常均匀的晶体尺寸，范围为8至20微米。傅里叶变换红外(FTIR)光谱用于确定生物活性玻璃和玻璃陶瓷植入物暴露于模拟体液(SBF)溶液时羟基碳酸磷灰石(HCA)的形成速率。结晶并没有抑制结晶HCA层的形成，但结晶的起始时间从母体玻璃的10小时增加到100%结晶玻璃陶瓷的22小时。当结晶百分比≥60%时，表面反应速率较慢。
