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特罗姆瑟心脏研究:高胆固醇血症男性的咖啡摄入量与血清脂质浓度:一项随机干预研究。

The Tromsø heart study: coffee consumption and serum lipid concentrations in men with hypercholesterolaemia: an randomised intervention study.

作者信息

Førde O H, Knutsen S F, Arnesen E, Thelle D S

出版信息

Br Med J (Clin Res Ed). 1985 Mar 23;290(6472):893-5. doi: 10.1136/bmj.290.6472.893.

Abstract

In a 10 week trial to assess the effects of coffee consumption and coffee brewing methods on serum cholesterol concentrations 33 men with hypercholesterolaemia were randomly assigned to: continue with their usual coffee intake; stop drinking coffee altogether; or stop drinking coffee for five weeks, thereafter drinking either boiled or filter coffee. Cholesterol concentrations fell significantly in all subjects abstaining for the first five weeks compared with subjects not giving up and continued to fall in those abstaining for 10 weeks. Cholesterol concentrations rose again in subjects returning to boiled coffee but remained the same in those returning to filter coffee. Abstention from heavy coffee drinking is an efficient way of reducing serum cholesterol concentrations in men with hypercholesterolaemia. The extent to which the brewing method affects this relation requires further study.

摘要

在一项为期10周的试验中,为评估咖啡摄入量及咖啡冲泡方法对血清胆固醇浓度的影响,33名高胆固醇血症男性被随机分为:继续按其平常的咖啡摄入量饮用;完全停止饮用咖啡;或停止饮用咖啡5周,之后饮用煮咖啡或过滤咖啡。与未放弃饮用咖啡的受试者相比,在前五周内所有 abstaining 的受试者胆固醇浓度均显著下降,且在 abstaining 10周的受试者中继续下降。恢复饮用煮咖啡的受试者胆固醇浓度再次上升,但恢复饮用过滤咖啡的受试者胆固醇浓度保持不变。对于高胆固醇血症男性而言,避免大量饮用咖啡是降低血清胆固醇浓度的有效方法。冲泡方法对这种关系的影响程度有待进一步研究。 (注:原文中abstaining在上下文中推测可能是“ abstaining from coffee”即“停止饮用咖啡”的意思,但此处直接翻译为“abstaining”不太准确,可根据实际情况修正完善译文)

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/375e/1417717/02114e45fc31/bmjcred00439-0023-a.jpg

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