Department of Mathematical Sciences, Montana State University, Bozeman, MT, USA.
NPJ Syst Biol Appl. 2024 Aug 28;10(1):98. doi: 10.1038/s41540-024-00423-8.
In this review paper we summarize a recent progress on the problem of describing range of dynamics supported by a network. We show that there is natural connection between network models consisting of collections of multivalued monotone boolean functions and ordinary differential equations models. We show how to construct such collections and use them to answer questions about prevalence of cellular phenotypes that correspond to equilibria of network models.
在这篇综述论文中，我们总结了网络所支持的动态范围描述问题的最新进展。我们表明，由多值单调布尔函数集合组成的网络模型与常微分方程模型之间存在自然联系。我们展示了如何构建这样的集合，并利用它们来回答关于对应于网络模型平衡点的细胞表型普遍性的问题。
