整合信号通路与转录因子网络——追寻西西弗斯？
Integrating Signaling Pathways with Transcription Factor Networks-On the Trail of Sisyphus?
机构信息
First Department of Respiratory Medicine, "Sotiria" Hospital, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.
Department of Biological Chemistry, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.
出版信息
Biomolecules. 2024 Aug 16;14(8):1015. doi: 10.3390/biom14081015.
Abstract
In the context of health and disease research, cells use signaling pathways that transduce stimuli from the extracellular environment to modulate intracellular gene expression via the activity of transcription factors and cofactors (coactivators and/or corepressors) [...].
摘要
在健康和疾病研究的背景下，细胞利用信号通路将来自细胞外环境的刺激转导到细胞内，通过转录因子和辅助因子（共激活因子和/或共抑制因子）的活性来调节基因表达[... ]。
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