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吸入式给药装置:重新审视哮喘管理的关键要素

Inhalational Drug Devices: Revisiting the Linchpin of Asthma Management.

作者信息

Saxena Damini, Murugesan Neveda, Evbayiro Uyioghosa D, Ngassa Marina K, Adrish Muhammad

机构信息

Baylor College of Medicine, Section of Pulmonary, Critical Care, and Sleep Medicine, 1 Baylor Plz, Houston, TX 77030, USA.

Baylor College of Medicine, Section of General Internal Medicine, 1 Baylor Plz, Houston, TX 77030, USA.

出版信息

J Pers Med. 2024 Aug 16;14(8):867. doi: 10.3390/jpm14080867.

Abstract

Asthma remains a prevalent condition among all age groups globally. First-line treatment requires the delivery of medications into the distal respiratory tract via inhalers. Using appropriate inhaler techniques is a significant challenge in achieving disease control. A variety of inhalers are available for treating asthma, and selecting the appropriate inhaler type for any given patient is crucial to achieving and maintaining symptomatic control. This review will discuss the anatomy and physiology behind drug delivery via inhalers, the types of inhalers currently available for use, nebulizers, and future directions in the delivery of inhaled medications for asthma.

摘要

哮喘在全球所有年龄组中仍然是一种普遍存在的疾病。一线治疗需要通过吸入器将药物输送到远端呼吸道。掌握合适的吸入器使用技巧是实现疾病控制的一项重大挑战。有多种吸入器可用于治疗哮喘,为任何特定患者选择合适的吸入器类型对于实现和维持症状控制至关重要。本综述将讨论通过吸入器给药背后的解剖学和生理学、目前可用的吸入器类型、雾化器以及哮喘吸入药物给药的未来方向。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/51af/11355058/bb42426fec57/jpm-14-00867-g001.jpg

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