Gao Zhaorong, Guo Zhen, Song Yongbo, Shi Xiujing, Zhao Yingzuo, Liu Conghui
Qingdao Eye Hospital of Shandong First Medical University, Eye Institute of Shandong First Medical University, Qingdao, People's Republic of China.
State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Eye Institute of Shandong First Medical University, Qingdao Eye Hospital of Shandong First Medical University, Qingdao, People's Republic of China.
Nat Sci Sleep. 2024 Sep 2;16:1303-1312. doi: 10.2147/NSS.S476051. eCollection 2024.
With girls typically exhibiting higher rates of myopia than boys, however, the mechanisms behind this gender difference remain unclear. This study aims to investigate the gender disparities in the relationship between myopia, sleep duration, physical activity, and BMI.
A total of 3138 primary and secondary school students were included. Mplus 8.3 was used to perform the multiple mediation analysis.
Sleep duration was indicated to directly affect myopia (β=0.273, 95% CI=0.184-0.356) and through physical activity, BMI, physical activity and BMI three significantly mediation pathways, respectively. In terms of gender, the mediating direct effect of sleep duration on myopia of boys was 66.96%, which is much higher than that of girls' 50.91%. And the mediating indirect effect of sleep duration on myopia through physical activity and BMI are 32.65% and 12.10% respectively among girls, both of which are significantly higher than that of boys.
The study found that there are significant differences in the impact of sleep duration on myopia in children and adolescents of different genders. In this regard, while paying attention to the sleep duration of children and adolescents, special attention should also be paid to the indirect impact of girls' physical activity and BMI on myopia, and targeted measures should be formulated according to children of different genders to effectively protect the eye health of children and adolescents.
然而，女孩的近视率通常高于男孩，这种性别差异背后的机制尚不清楚。本研究旨在调查近视、睡眠时间、体育活动和体重指数之间关系中的性别差异。
共纳入3138名中小学生。使用Mplus 8.3进行多重中介分析。
睡眠时间被表明直接影响近视（β=0.273，95%CI=0.184-0.356），并分别通过体育活动、体重指数、体育活动和体重指数这三条显著的中介途径影响近视。在性别方面，睡眠时间对男孩近视的中介直接效应为66.96%，远高于女孩的50.91%。女孩中睡眠时间通过体育活动和体重指数对近视的中介间接效应分别为32.65%和12.10%，均显著高于男孩。
研究发现睡眠时间对不同性别的儿童和青少年近视的影响存在显著差异。对此，在关注儿童和青少年睡眠时间的同时，还应特别关注女孩体育活动和体重指数对近视的间接影响，并针对不同性别的儿童制定有针对性的措施，以有效保护儿童和青少年的眼健康。
