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在青少年大脑认知发展(ABCD)研究中,对初涉酒精的青少年的酒精预期进行纵向追踪及其与冲动性的关联。

Longitudinal tracking of alcohol expectancies and their associations with impulsivity in alcohol naïve youth in the adolescent brain cognitive development (ABCD) study.

作者信息

Adams Faith, Ferster Karmiella S, Morris Laurel S, Potenza Marc N, Ivanov Iliyan, Parvaz Muhammad A

机构信息

Department of Neuroscience, Icahn School of Medicine at Mount Sinai (ISMMS), New York, NY, United States.

Department of Psychiatry, ISMMS, New York, NY 10029, United States.

出版信息

Drug Alcohol Depend Rep. 2024 Aug 10;12:100271. doi: 10.1016/j.dadr.2024.100271. eCollection 2024 Sep.

DOI:10.1016/j.dadr.2024.100271
PMID:39262669
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11387828/
Abstract

BACKGROUND

Positive and negative alcohol expectancies (PAEs and NAEs, respectively) and impulsivity are key risk factors for the onset of alcohol use. While both factors independently contribute to alcohol initiation, the developmental aspects of AEs and their nuanced relationship with impulsivity are not adequately understood. Understanding these relationships is imperative for developing targeted interventions to prevent or delay alcohol use onset in youth.

METHODS

This study utilized the Adolescent Brain Cognitive Development cohort to examine how PAEs and NAEs develop over time and relate to each other. We also explored how self-reported and behavioral impulsivity at baseline (~10 years old) are associated with the longitudinal development of PAEs and NAEs in youth Ages 11, 12, and 13 (n = 7493; 7500; and 6981, respectively), as well as their time-specific relationships.

RESULTS

Findings revealed while PAEs increased steadily over all three years, NAEs increased from ages 11-12 and then remained unchanged between 12 and 13. Overall, PAEs and NAEs were inversely related. Moreover, PAEs positively correlated with sensation seeking and lack of premeditation, while NAEs negatively correlated with positive urgency. Interestingly, a time-specific association was observed with PAEs and lack of perseverance, with a stronger correlation to PAEs at Age 11 compared to Age 12.

CONCLUSIONS

Overall, this study provides valuable insights into the divergent developmental trajectory of PAEs and NAEs, and their overall and time-specific associations with impulsivity. These findings may guide focused and time-sensitive prevention and intervention initiatives, aiming to modify AEs and reduce underage drinking.

摘要

背景

积极和消极的酒精预期(分别为PAEs和NAEs)以及冲动性是酒精使用开始的关键风险因素。虽然这两个因素都独立地促成了酒精的开始使用,但酒精预期的发展方面及其与冲动性的细微关系尚未得到充分理解。了解这些关系对于制定有针对性的干预措施以预防或延迟青少年酒精使用的开始至关重要。

方法

本研究利用青少年大脑认知发展队列来研究PAEs和NAEs如何随时间发展以及它们之间的相互关系。我们还探讨了在基线时(约10岁)自我报告的和行为上的冲动性如何与11岁、12岁和13岁青少年(分别为n = 7493;7500;和6981)的PAEs和NAEs的纵向发展相关,以及它们特定时间的关系。

结果

研究结果显示,虽然PAEs在所有三年中稳步增加,但NAEs在11 - 12岁时增加,然后在12 - 13岁之间保持不变。总体而言,PAEs和NAEs呈负相关。此外,PAEs与寻求刺激和缺乏预谋呈正相关,而NAEs与积极紧迫性呈负相关。有趣的是,观察到PAEs与缺乏毅力存在特定时间的关联,与11岁时的PAEs相关性比12岁时更强。

结论

总体而言,本研究为PAEs和NAEs不同的发展轨迹以及它们与冲动性的总体和特定时间的关联提供了有价值的见解。这些发现可能指导有针对性的和对时间敏感的预防和干预措施,旨在改变酒精预期并减少未成年人饮酒。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a47/11387828/56e6f6fb373e/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a47/11387828/001946f009e8/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a47/11387828/48bdd2c2674f/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a47/11387828/56e6f6fb373e/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a47/11387828/001946f009e8/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a47/11387828/48bdd2c2674f/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a47/11387828/56e6f6fb373e/gr3.jpg

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本文引用的文献

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Change in alcohol outcome expectancies from childhood to emerging adulthood: A meta-analysis of longitudinal studies.从儿童期到成年早期的酒精预期结果变化:纵向研究的元分析。
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Hyperbolic discounting rates and risk for problematic alcohol use in youth enrolled in the Adolescent Brain and Cognitive Development study.
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