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口腔多形红斑:一例报告及对诊断、治疗和预后挑战的综述

Oral Erythema Multiforme: A Case Report and Review of Diagnostic, Therapeutic and Prognostic Challenges.

作者信息

M Deivanayagi, Chandran Narmadha, B Elamparithi, S Sakthi, A R Thennarasu

机构信息

Oral Medicine and Radiology, Adhiparasakthi Dental College and Hospital, Melmaruvathur, IND.

Oral and Maxillofacial Surgery, Adhiparasakthi Dental College and Hospital, Melmaruvathur, IND.

出版信息

Cureus. 2024 Aug 13;16(8):e66749. doi: 10.7759/cureus.66749. eCollection 2024 Aug.

DOI:10.7759/cureus.66749
PMID:39268324
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11391332/
Abstract

Erythema multiforme (EM) presents a distinct challenge in both diagnosis and management, particularly when its manifestations extend to the oral cavity. Classified into "minor" and "major" forms based on clinical presentation, EM defies gender bias and tends to affect individuals across different age groups. The complexity arises from its varied symptoms within the oral cavity, where it commonly manifests as painful, red erosive plaques known as target lesions, primarily observed on the lips and oral mucosa. These lesions may arise independently or be linked to underlying systemic or infectious conditions, complicating the diagnostic process. Here, we present a case study of a 55-year-old female patient grappling with EM, underscoring the importance of meticulous clinical examination, thorough investigations, tailored treatment strategies, and subsequent outcomes.

摘要

多形红斑(EM)在诊断和治疗方面都面临着独特的挑战,尤其是当其表现累及口腔时。根据临床表现,EM分为“轻型”和“重型”,它不存在性别差异,且往往会影响不同年龄组的个体。其复杂性源于口腔内症状多样,通常表现为疼痛的红色糜烂斑块,即靶形损害,主要见于唇部和口腔黏膜。这些损害可能独立出现,也可能与潜在的全身或感染性疾病有关,这使得诊断过程变得复杂。在此,我们呈现一例55岁女性多形红斑患者的病例研究,强调细致的临床检查、全面的检查、个性化的治疗策略及后续结果的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ee1/11391332/ec7af550890b/cureus-0016-00000066749-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ee1/11391332/4be944e4b33c/cureus-0016-00000066749-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ee1/11391332/82d28f5e1ede/cureus-0016-00000066749-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ee1/11391332/ca6306856295/cureus-0016-00000066749-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ee1/11391332/ec7af550890b/cureus-0016-00000066749-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ee1/11391332/4be944e4b33c/cureus-0016-00000066749-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ee1/11391332/82d28f5e1ede/cureus-0016-00000066749-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ee1/11391332/ca6306856295/cureus-0016-00000066749-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ee1/11391332/ec7af550890b/cureus-0016-00000066749-i04.jpg

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本文引用的文献

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2
Recent Updates in the Treatment of Erythema Multiforme.多形红斑的治疗新进展。
Medicina (Kaunas). 2021 Sep 1;57(9):921. doi: 10.3390/medicina57090921.
3
Erythema Multiforme Attributable to Herpes Simplex Virus: Clinical Aspects and Treatment.单纯疱疹病毒所致多形红斑:临床特征与治疗
Case Rep Dent. 2021 May 10;2021:6692495. doi: 10.1155/2021/6692495. eCollection 2021.
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Rowell Syndrome: A Diagnostic Challenge.罗威尔综合征:一项诊断挑战。
J Clin Aesthet Dermatol. 2020 Apr;13(4):40-42. Epub 2020 Apr 1.
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A fatal case of COVID-19 infection presenting with an erythema multiforme-like eruption and fever.一例出现多形红斑样皮疹和发热的新型冠状病毒肺炎死亡病例。
Dermatol Ther. 2020 Jul;33(4):e13779. doi: 10.1111/dth.13779. Epub 2020 Jul 1.
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Erythema Multiforme: Recognition and Management.多形红斑:识别与管理。
Am Fam Physician. 2019 Jul 15;100(2):82-88.
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J Eur Acad Dermatol Venereol. 2019 May;33(5):842-849. doi: 10.1111/jdv.15447. Epub 2019 Feb 28.
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